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“An evolutionary perspective also contributes to explain the higher female prevalence of panic disorder and agoraphobia. On average, women are more physically vulnerable than men and less able to defend themselves against attacks. Accordingly, it is adaptive for them to be more sensitive to potential cues of vulnerability and entrapment, and display a lower threshold for the activation of escape behaviors.” — Marco del Giudice

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An evolutionary perspective also contributes to explain the higher female prevalence of panic disorder and agoraphobia. On average, women are more physically vulnerable than men and less able to defend themselves against attacks. Accordingly, it is adaptive for them to be more sensitive to potential cues of vulnerability and entrapment, and display a lower threshold for the activation of escape behaviors.
— Marco del Giudice