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“Why Is It So Hard to Lose Weight? Body fat is hard to lose because the body automatically burns the easiest energy source first—blood glucose; when blood glucose gets too low, the body then uses the next easiest source of energy—glycogen in the liver—which converts back to glucose and goes into the bloodstream. Then and only then, after the liver is depleted of glycogen, does the body begin to use body fat. That is why body fat is so hard to get rid of. It’s the last source of energy used and is also a very stable molecule that is hard to break down. You can gain weight easily simply by putting more glucose in your bloodstream than you need for your current activity or inactivity. But it’s harder to lose weight because body fat is the last source of energy your body uses. This is the very reason that you can gain weight quickly, but losing weight takes longer.” — Rick Mystrom