“higher antimicrobial loads will result in a lower total pathogenic load but also a lower involvement of the immune system and therefore less immunity in the long run (as indeed has been empirically demonstrated in a number of experiments summarised in a sweeping review by Benoun (2016)). Thus, while rapid and aggressive antimicrobial treatment is sometimes appropriate, the long-term absence of ensuing CD4+ immunity is its cost.” Immune SystemAntibioticsEpidemiologyImmunologyAntibiotic Resistance Book:Computational Modeling of Infectious Disease: With Applications in Python Source: Computational Modeling of Infectious Disease: With Applications in Python