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Edward Boyden

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“I would argue that if you understand how the cells of the brain are organized into circuits, almost computational circuits if you will, and we see how information flows through those circuits and how it's transformed, we might have a much firmer grasp on why our brains make decisions the way that they do. If we get a handle on that, maybe we can overcome some of our limitations and at the very least we'll understand why we do what we do.”

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“The brain is really hard to see. The whole thing is very large - the human brain is several pounds in weight - but the connections between brain cells, known as synapses, are really tiny. They're nanoscale in dimension. So if you want to see how the cells of the brain are connected in networks, you have to see those connections, those synapses.”

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“For the last century of neuroscience, lots of people have tried to control neurons using all sorts of different technologies - pharmacology (drugs), electrical pulses, and so on. But none of these technologies are precise. With optogenetics, we can aim light at a single cell, or a set of cells, and turn just that set of cells on or off.”

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