“It would be indeed unusual if it turned out that the set of orders that our mind is able to construct and accept, having as it does a deep sense of “understanding the essence of things,” matches precisely the set of all possible orders to be detected in the Universe as a whole. We should admit that this is not impossible, yet it does seem highly improbable. This way of thinking, so modest in its assessment of our abilities, is probably the only way recommended, given our lack of knowledge, because we are not aware of our limitations.”
Book:Summa technologiae