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Quote by John Roberts

“End-stage liver disease refers to a liver that's failing, and a very high percentage of those livers are what we call cirrhotic, or the patient's liver has become cirrhotic, and what cirrhosis is, is the scarring of the liver tissue.”

Quote by John Roberts

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John Roberts
John Roberts

John Roberts, born on January 27, 1955, is the Chief Justice of the United States Supreme Court. He is highly respected in the legal community and has served as a judge on the U.S. Court of Appeals. Appointed by President George W. Bush in 2005, Roberts has had a significant impact on the American judicial system. more

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“There are many different causes of the scarring. Viruses are common. Hepatitis B, hepatitis C, what we call autoimmune diseases where the body attacks the liver itself such as primary biliary cirrhosis is an autoimmune disease; sclerosing cholangitis is an autoimmune disease; and so those diseases where the liver is being destroyed by either the virus or an autoimmune disease, it can only scar, and why it doesn't regenerate has to do with the fact that there is this ongoing scar tissue that blocks that regeneration.”

“When a liver becomes cirrhotic, those are the common complications. We see that the patients have bleeding from their stomach and intestines. They have abdomens that become full of fluid. Their ankles swell with the same type of fluid, and they also can become confused and not themselves. Those are kind of the main things that we see when people get end-stage liver disease and have cirrhosis.”

“There is a risk of death associated with donating a piece of liver. It's about one in 500 for the risk of death. The risk of death of donating a kidney is about one in 3000, so this is a riskier operation than donating a kidney. The stakes are usually higher for the recipient of the transplant because unlike kidney failure, where you have a dialysis machine, in liver failure we don't have that kind of machine that allows a patient to survive until they can get a cadaver organ.”