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Quote by C. Vivian Stringer

“Life might be unfair; you might be blindsided by bad luck or misfortune. Nobody knows better than a basketball coach that you might not reap the rewards of your hard work, and that you don't always get what you deserve. But with the support of other people, you get through it. We need one another, and if we stick together, we can get through anything.”

Book:Standing Tall: A Memoir of Tragedy and Triumph

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Standing Tall: A Memoir of Tragedy and Triumph

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Author

C. Vivian Stringer

C. Vivian Stringer is a distinguished basketball coach who has made significant contributions to the sport, particularly in women's basketball. With a coaching career spanning over four decades, she has been a pivotal figure in shaping the landscape of women's basketball. Stringer has led her teams to numerous national championships and has been honored with numerous awards for her coaching excellence. more

“ERV envelope genes possess unique properties that make them suitable for use in forming the placenta: they are fusogenic proteins and they have immunosuppresive properties. Eutherian (placental) mammals distinguish themselves from nonplacental animals in the ability of the female to nurture the fertilized ovum and growing embryo within the body. The placenta is a transient tissue of embryonic origin whose evolution made it unnecessary to partition the embryo into a protective egg, which matured outside the mother's body. It serves two purposes for the maturing embryo: it is a conduit for respiratory gasses and nourishment supplied by the mother, and it provides an environment of immune tolerance. The fetus is necessarily half-foreign tissue, an allograft within the mother. It draws half of its genetic, and hence antigenic, identity from maternal and half from paternal genes. If the fetus is to mature within the mother, it must be isolated from the maternal immune system such that a graft-versus-host response does not reject it. The placenta forms early after implantation of the embryo. Syncytins mediate the formation of a continuous fused layer of cells around the embryo, isolating it from the mother, yet allowing essential nutrients to traverse from the mother's system. Although the observations on human syncytin-1 and -2 were compelling, it was left to scientists to definitively link syncytins to placental formation by studying mice. Here two syncytins (dubbed A and B) from murine ERVs were implicated, and genetic experiments with mice defective in these genes confirmed that their dysfunction disrupted placental formation. Notably, however, syncytin-A and -B were not syntenic with the human syncytins. That is, the human and mouse genes are not descended fron common ancestral syncytins; they have arisen by separate ERV gene capture events from different families of ERV in human and mouse ancestors.”

Placenta Embryo Erv Retroviral Proteins Syncytins

Book:Viruses: Agents of Evolutionary Invention

Source: Viruses: Agents of Evolutionary Invention

“In her enthralling debut, Circle of Chalk, Christina McClelland tackles the complicated and sometimes controversial subject of IVF with compassion and honesty. McClelland doesn’t shy away from the messiness but rather invites the reader into the decades’ long journey. The story twists and turns until the very last page. Elizabeth Musser, author of The Swan House, When I Close My Eyes, The Promised Land”

Science Fiction Fertility Infertility Medical Ethics Ivf Embryo

Author:Elizabeth Musser

“It is extraordinarily entertaining to watch the historians of the past ... entangling themselves in what they were pleased to call the "problem" of Queen Elizabeth. They invented the most complicated and astonishing reasons both for her success as a sovereign and for her tortuous matrimonial policy. She was the tool of Burleigh, she was the tool of Leicester, she was the fool of Essex; she was diseased, she was deformed, she was a man in disguise. She was a mystery, and must have some extraordinary solution. Only recently has it occrurred to a few enlightened people that the solution might be quite simple after all. She might be one of the rare people were born into the right job and put that job first.”