“It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body. The time may come when penicillin can be bought by anyone in the shops. Then there is the danger that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant.” MenMayBodyDifficultHappenedDangerDrugIgnorantSufficientShopsConcentrationQuantityLaboratoryExposingMicrobesPenicillin Author:Alexander Fleming
“I have been trying to point out that in our lives chance may have an astonishing influence and, if I may offer advice to the young laboratory worker, it would be this-never neglect an extraordinary appearance or happening. It may be-usually is, in fact-a false alarm that leads to nothing, but may on the other hand be the clue provided by fate to lead you to some important advance.” IfsTryingMayHas BeensImportantFactsHandsWould BeYoungScienceChanceOur LivesFateInfluenceAdviceOffersHappeningsDiscoveryLuckExtraordinaryWorkersAppearanceNeglectClueAstonishingLaboratoryAlarmsPenicillin Author:Alexander Fleming
“It is the lone worker who makes the first advance in a subject: the details may be worked out by a team, but the prime idea is due to the enterprise, thought, and perception of an individual.” FirstsMayIdeasScienceIndividualTeamSubjectsPerceptionDiscoveryWorkersIndividualityDetailsDuesEnterprisePrimeCollaborationLonePenicillin Author:Alexander Fleming
“It has been demonstrated that a species of penicillium produces in culture a very powerful antibacterial substance which affects different bacteria in different degrees. Generally speaking it may be said that the least sensitive bacteria are the Gram-negative bacilli, and the most susceptible are the pyogenic cocci ... In addition to its possible use in the treatment of bacterial infections penicillin is certainly useful... for its power of inhibiting unwanted microbes in bacterial cultures so that penicillin insensitive bacteria can readily be isolated.” MayHas BeensSaidDifferentUseCulturePowerfulProduceDegreesNegativeSpeciesSubstanceSensitiveTreatmentIsolatedVery PowerfulInfectionSusceptibleUnwantedInsensitiveBacteriaMicrobesPenicillin Author:Alexander Fleming