“Malaise” is a general body discomfort or weakness, often marking the onset of an of infection/flu-like illness or other disease. Fatigue and flu-like symptoms are linked to activation of the immune system and research scientists are in the process of unraveling these mechanisms in ME/CFS.” CfsChronic Fatigue SyndromeMyalgic EncephalomyelitisMalaiseM E CfsM EPost Exertional Malaise Author:Alison C. Bested