“The pathophysiological consequences of ME/CFS are multi-systemic and may include: immune and neuroendocrine abnormalities; brain dysfunction and neurocognitive defects; cardiovascular and autonomic disturbances; abnormalities in energy production including mitochondrial dysfunction, and changes in the expression of certain genes.” CfsChronic Fatigue SyndromeMyalgic EncephalomyelitisMe CfsNeurological Problems Author:Anthony Komaroff
“CBT is a much publicised and debated psychotherapeutic intervention for ME/CFS….The premise that cognitive therapy (eg. changing ‘illness beliefs’) and graded activity can ‘reverse’ or cure this illness is not supported by post-intervention outcome data. In routine medical practice, CBT has not yielded clinically significant outcomes for patients with ME/CFS.” CfsChronic Fatigue SyndromeMyalgic EncephalomyelitisMe CfsCognitive Behavioral TherapyGraded Exercise TherapyInvisible Illness StigmaCbtIllness BeliefsGraded ExerciseIatrogenic Harm Author:Anthony Komaroff