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“To the extent that psychological mechanisms rely on information acquired through learning, they are vulnerable to maladaptive outcomes owing to the intrinsic limitations of learning processes. Indeed, the massive capacity for individual and social learning required to exploit the cognitive niche may contribute to explain our species' seemingly unique vulnerability to mental disorders.”

“Evolutionary mismatch may occur when an evolved mechanism encounters a novel environmental context that falls outside of the range that was recently encountered over its evolutionary history (the EEA or environment of evolutionary adaptation). In the new context, a functional mechanism can give rise to maladaptive outcomes or even induce dysfunctions in other mechanisms.”

“In modern societies, for example, the media expose people to a relentless stream of images of unrealistically attractive "competitors" -an artificial, evolutionarily novel kind of social stimulus. It has been hypothesized that such exposure hyperactivates the evolved mechanisms that regulate female competition for attractiveness and status, thus contributing to the rising incidence of eating disorders.”

“For instance, people who form early representations of the world as dangerous or uncontrollable may become anxious and start avoiding situations that they perceive as threatening. Avoidance is usually an adaptive response to danger; in this case, however, it prevents anxious individuals from learning that the environment is actually safer than they believe, thus locking them in a state of exaggerated anxiety. Even if such catastrophic failures of learning mechanisms are statistically rare, they can be highly maladaptive for the individuals who experience them.”

“Defensive mechanisms can make two symmetric kinds of mistakes: they can fail to activate in the presence of a threat (false negatives) or become activated when no threat is present (false positives). Even when defenses are functional and optimally calibrated, errors cannot be completely avoided; given the tradeoffs between the costs of different types of errors, the smoke detector principle suggests that defensive systems should typically evolve to commit more false positives than false negatives.”