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“Starting from middle childhood, however, boys and girls begin to take part in different social worlds with specific sets of challenges; moreover, sex differences in muscle mass and strength, bone density, and adiposity become more pronounced, giving boys a definite advantage in dealing with physical danger.”

“Evolutionary scholars have long stressed the adaptive role of aggressive and antisocial behavior as a high-risk strategy for social and mating competition. In evolutionary psychopathology, antisocial disorders are usually regarded as costly but potentially adaptive strategies rather than behavioral dysfunctions. Some authors have focused specifically on the evolution of psychopathy, and argued that this condition embodies a "cheater" social strategy designed to exploit other people's trust and cooperative behavior while avoiding reciprocation.”

“Disorders in the psychosis spectrum (schizophrenia spectrum disorder and dipolar disorder) have similar prevalance in males and females (with slightly higher male risk for schizophrenia), while men are more likely to be diagnosed with NPS (narcissistic personality disorder) than are women.”

“Evolution in the cognitive niche has endowed our species with remarkable abilities such as language, abstract reasoning, and sophisticated mentalizing. These species-typical innovations have been accompanied by rapid changes in brain structure and functionality. While adaptations such as language are hugely beneficial, they are also likley to carry some costs. A number of authors have argued that vulnerability to psychosis is one of those costs -the price our species pays for its unique set of cognitive skills. From this perspective, there are no individual fitness benefits to psychosis proneness; vulnerability to schizophrenia and other psychoses is a general byproduct of our evolved design, and unfortunate combinations of genetic and environmental factors determine the onset of a full-fledged disorder in some individuals.”

“Even properly functioning defenses are subject to activation errors, evolutionary/developmental mismatches and maladaptive learning; moreover, mechanisms that are initially functional may become damaged or dysregulated following periods of chronic hyperactivation. In other words, conditions that start as adaptive response may sometimes morph into dysfuntions along the way.”

“As a rule, sexually selected traits tend to be more condition-dependent --and thus more vulnerable to dysfunctions-- than other phenotypes. This contributes to explain why males are generally more vulnerable to both harmful mutations and environmental insults.”

“All biological and artificial mechanisms -no matter how well designed- are vulnerable to malfunctions, failures, and breakdowns. Even if developmental processes are canalized against perturbations, they can deviate from their target phenotype as random events and disturbances accumulate over time.”