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Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry

Book by Randolph M. Nesse · 8 quotes · Psychopathology, Evolutionary Psychology, Mismatch

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Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry Quotes

“Treatment of eating disorders is improved by the recognition that strenuous dieting arouses famine protection mechanisms that are prone to initiate a positive feedback spiral.”

“Eating disorders were not shaped by selection, but mechanisms that regulate eating during famines were. ADHD was not shaped by selection, but mechanisms that regulate attention were. Serious depression was not shaped by natural selection, but capacities for normal low and high mood were.”

“Patients with anorexia nervosa and bulimia nervosa are surrounded by excess food, but their bodies are aware only of starvation. Their behavior is appropriate for a situation in which getting just a few extra calories might make the difference between life and death.”

“The starting point is recognizing that selection has shaped powerful mechanisms to protect against starvation. During a famine, those mechanisms motivate animals to get food -any food- eat it quickly, and eat more than usual, because food supplies are obviously erratic. The system also adjusts the body weight set point upward because extra fat stores are valuable when food sources are unreliable. And, as noted already, weight loss slows down metabolism, which is appropriate when a person is starving but the opposite of what is needed when trying to lose weight. Also, intermittent access to food signals unreliable access to food supplies, so it increases food intake and bingeing, even in rats.”

“Criminalization and interdiction have filled prisons and corrupted governments in country after country. However, increasingly potent drugs that can be synthetized in any basement make controlling access increasingly impossible. Legalization seems like a good idea but causes more addiction. Our strongest defense is likely to be education, but scare stories make kids want to try drugs. Every child should learn that drugs take over the brain and turn some people into miserable zombies and that we have no way to tell who will get addicted the fastest. They should also learn that the high fades as addiction takes over.”

“Most chemicals that give humans a buzz evolved to disrupt insect nervous systems. If our brains used different chemicals, we would not be so vulnerable. However, we have common ancestors with insects. It was long ago, about 500 million years ago, when our ancestors split off from the arthropod lines that became modern insects. However, our neurochemicals remain about the same as theirs. Fortunately, most plant neurotoxins don’t kill us. We have evolved to eat plants, and we are much larger than insects, so low doses are not fatal. But drugs can hijack our motivation mechanisms and take control of our lives.”

“The trajectory is clear: our minds have always been vulnerable to capture by alcohol, marijuana, tobacco, coca, and opium, but problems with them have escalated as advances in chemistry, transportation, and technology have increased the diversity, purity, and availability of drugs. The mismatch was bad before; now it’s getting much worse.”