Tom J. Donohue (born 1938) is a prominent American business leader who served as the president and CEO of the U.S. Chamber of Commerce from 1997 to 2021. He is known for his influential role in business advocacy, policy shaping, and international trade. Donohue began his career in education before transitioning to association management, becoming one of the most powerful business lobbyists in the United States. Under his leadership, the Chamber expanded its membership and global reach, advocating for free trade, regulatory reform, and tax policies favorable to businesses.