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Quote by Paul R. Fournier

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Anonymous Cultures, The Silent Majority: Strategies in Culture Management and Leadership

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Paul R. Fournier

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“Life might be unfair; you might be blindsided by bad luck or misfortune. Nobody knows better than a basketball coach that you might not reap the rewards of your hard work, and that you don't always get what you deserve. But with the support of other people, you get through it. We need one another, and if we stick together, we can get through anything.”

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“ERV envelope genes possess unique properties that make them suitable for use in forming the placenta: they are fusogenic proteins and they have immunosuppresive properties. Eutherian (placental) mammals distinguish themselves from nonplacental animals in the ability of the female to nurture the fertilized ovum and growing embryo within the body. The placenta is a transient tissue of embryonic origin whose evolution made it unnecessary to partition the embryo into a protective egg, which matured outside the mother's body. It serves two purposes for the maturing embryo: it is a conduit for respiratory gasses and nourishment supplied by the mother, and it provides an environment of immune tolerance. The fetus is necessarily half-foreign tissue, an allograft within the mother. It draws half of its genetic, and hence antigenic, identity from maternal and half from paternal genes. If the fetus is to mature within the mother, it must be isolated from the maternal immune system such that a graft-versus-host response does not reject it. The placenta forms early after implantation of the embryo. Syncytins mediate the formation of a continuous fused layer of cells around the embryo, isolating it from the mother, yet allowing essential nutrients to traverse from the mother's system. Although the observations on human syncytin-1 and -2 were compelling, it was left to scientists to definitively link syncytins to placental formation by studying mice. Here two syncytins (dubbed A and B) from murine ERVs were implicated, and genetic experiments with mice defective in these genes confirmed that their dysfunction disrupted placental formation. Notably, however, syncytin-A and -B were not syntenic with the human syncytins. That is, the human and mouse genes are not descended fron common ancestral syncytins; they have arisen by separate ERV gene capture events from different families of ERV in human and mouse ancestors.”

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“In her enthralling debut, Circle of Chalk, Christina McClelland tackles the complicated and sometimes controversial subject of IVF with compassion and honesty. McClelland doesn’t shy away from the messiness but rather invites the reader into the decades’ long journey. The story twists and turns until the very last page. Elizabeth Musser, author of The Swan House, When I Close My Eyes, The Promised Land”

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“It is extraordinarily entertaining to watch the historians of the past ... entangling themselves in what they were pleased to call the "problem" of Queen Elizabeth. They invented the most complicated and astonishing reasons both for her success as a sovereign and for her tortuous matrimonial policy. She was the tool of Burleigh, she was the tool of Leicester, she was the fool of Essex; she was diseased, she was deformed, she was a man in disguise. She was a mystery, and must have some extraordinary solution. Only recently has it occrurred to a few enlightened people that the solution might be quite simple after all. She might be one of the rare people were born into the right job and put that job first.”

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“Langzaam zoom ik in en zie tegelijkertijd de drooggetrainde, wiegende rug van Madonna (‘Vogue’) en ik weet dat in de kooi van haar ribben, ingekapseld in taaie draden, haar hart klopt, als een glanzend oranje embryo. Om de een of andere reden stelt mij dat gerust en daarom laat ik de camera het plekje tussen haar schouderblad en ruggengraat viseren waarna ik in de badkamer verdwijn.”

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“You are your abilities and they are you. I can't put it to you more plainly. Do you know why I hate this cure? It's a statement that what we are is inherently wrong. It's a punishment for something that isn't our fault - all because they can't control their fear about what we can do, anymore than they can control their resentment that there are people out there stronger and more powerful than they are. They want to strip you of yourself - your ability to protect and enforce your right to make decisions about your life. Your own body. Mark my words: in the end, it won't be a choice. They'll decide this for you.”

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“I walked until I lost the light from the fire pit, clawing at my T-shirt, trying to pull it away from my skin. It smelled like his room. Like evergreens and spice and old, decaying things. I pulled it over my head and threw it as hard and far as I could, and still—still—I couldn’t shake the smell. It was everywhere: my hands, my jeans, my bra. I should have run straight for the lake, or even the showers. I should have tried to soak his venom out.”

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“Prior to the age of telegraphy, the information-action ratio was sufficiently close so that most people had a sense of being able to control some of the contingencies in their lives. What people knew about had action-value. In the information world created by telegraphy, this sense of potency was lost, precisely because the whole world became context for news. Everything became everyone's business. For the first time, we were sent information which answered no question we had asked, and which, in any case, did not permit the right of reply.”

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