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“You can change dopamine and the dorsal striatum with exercise. You can boost serotonin with a massage. You can make decisions and set goals to activate the ventromedial prefrontal cortex. You can reduce amygdala activity with a hug and increase anterior cingulate activity with gratitude. You can enhance prefrontal norepinephrine with sleep.”

“Go out in the sunlight. Bright sunlight helps boost the production of serotonin. It also improves the release of melatonin, which helps you get a better night’s sleep. So if you’re stuck inside, make an effort to go outside for at least a few minutes in the middle of the day. Go for a walk, listen to some music, or just soak in the sun.”

“Massage reduces pain because the oxytocin system activates painkilling endorphins. Massage also improves sleep and reduces fatigue by increasing serotonin and dopamine and decreasing the stress hormone cortisol. So if you’re feeling out of sorts, get a massage. You’ll be actively triggering the neurotransmitter systems that work to make you happier.”

“I was playing a lot of sports, and that actually changes dopamine signaling in the brain, which helps make life more enjoyable. And going to class not only altered the habit circuit in my brain, but it also meant that I had to spend some time out in the sun on my way to and from classes, which boosted my serotonin and regulated electrical activity in my brain during sleep.”

“Getting a massage is also a great way to relax your muscles. Massage reduces pain, stress, and anxiety, and it improves sleep. The wide-ranging effects likely result from the fact that massage boosts your serotonin and dopamine levels and decreases cortisol. Sometimes it’s even helpful to give yourself a massage with a tennis ball by lying on it, leaning against it, or rolling it firmly against your muscles. It probably doesn’t have all the same effects as getting a massage from a person, but it’s cheap and quick, and it can still feel great.”

“With each little bit of exercise I did, each time I chose to move a little more, everything became easier. My brain was juicing up on all those good neurochemicals—all that serotonin, dopamine, and norepinephrine began making things happen. The BDNF was silently working away. As a result, not only did I have a bigger appetite, but food tasted better, and I wanted to eat healthier foods. I didn’t worry about things as much, and my sleep improved. I felt like I had more free time and even felt younger. Then exercise became more appealing, and slowly I became intrigued by the thought of a marathon.”

“Your Dopamine System with Quality Sleep. The dopamine system helps modulate both slow-wave sleep and REM sleep.28 Furthermore, not only does dopamine have a large effect on sleep (as well as on pain and depression) but sleep, pain, and depression all also affect the dopamine system. In addition, many aspects of the dopamine system are influenced by circadian rhythms, including the production of dopamine receptors, dopamine transporters, and dopamine itself.”