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“During the initial agricultural -revolution-, people began to cultivate cereals, rice and other plants. They settled into permanent dwellings to tend crops and led more sedentary lifestyles. Some early agriculturalists decreased the breadth of their diet, incorporated more carbohydrates and lived in larger communities, where diseases could spread more easily.”

“Once industrialisation ocurred, non-communicable (chronic) diseases (NCDs; e.g., cancers, cardiovascular disease, diabetes, cardio-vascular, and non-infectious respiratory diseases) started to rise and replace infections. Tobacco use, physical inactivity, unhealthy diets and the harmful use of alcohol are key risk factors for NCDs.”

“The dramatic changes that occurred in the relationships between humans and animals as societies transitioned from hunting and foraging to herding and farming, and from living in rural to urban and industrialized environments, had major impacts on pathogen evolution. The development, spread and intensification of agriculture, coupled with urbanization and increased connectivity through trade, enhanced opportunities for pathogens to be shared. Populations of potential hosts, human and animal, were increasingly crowded together often in unsanitary environments. These conditions drove pathogen transmission and virulence because they facilitated transmission from heavily infected and very sick individuals.”