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Quote by Anna Lembke, MD

“Mindfulness practices are especially important in the early days of abstinence. Many of us use high-dopamine substances and behaviors to distract ourselves from our own thoughts. When we first stop using dopamine to escape, those painful thoughts, emotions, and sensations come crashing down on us. The trick is to stop running away from painful emotions, and instead allow ourselves to tolerate them. When we're able to do this, our experience takes on a new and unexpectedly rich texture. The pain is still there, but somehow transformed, seeming to encompass a vast landscape of communal suffering, rather than being wholly our own.”

Quote by Anna Lembke, MD

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Anna Lembke, MD

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“Serotonin—improves willpower, motivation, and mood. Norepinephrine—enhances thinking, focus, and dealing with stress. Dopamine—increases enjoyment and is necessary for changing bad habits. Oxytocin—promotes feelings of trust, love, and connection, and reduces anxiety. GABA—increases feelings of relaxation and reduces anxiety. Melatonin—enhances the quality of sleep. Endorphins—provide pain relief and feelings of elation. Endocannabinoids—improve your appetite and increase feelings of peacefulness and well-being.”

“Boosting serotonin leads to a better mood and a greater ability to set goals and avoid bad habits. Increasing norepinephrine means better concentration and lower stress. And more dopamine generally means more enjoyment.”

“Just ten minutes of exercise had significantly altered their dopamine circuits and increased their willpower. Yes, pedaling a couple miles on a stationary bike while reading the latest issue of People won’t solve all your problems, but for your brain, it’s a heckuva lot better than just sitting there, and it’s a great kick start to an upward spiral.”

“Setting Goals to Increase Dopamine. People are often at their best when working toward a long-term, meaningful goal that they believe is achievable, like earning a degree or getting a promotion. That’s because not only is dopamine released when you finally achieve a long-term goal but it’s also released with each step you make as you move closer to achieving it. Having a goal also allows the prefrontal cortex to more effectively organize your actions. And most importantly, achieving the goal is often less important to happiness than setting the goal in the first place.”

“Another study showed that humor appreciation also activates the dopamine-rich nucleus accumbens, as well as the brain stem region that produces dopamine, which explains the enjoyable aspect of humor. It also activates areas of the dorsal striatum, which suggests that there is something habitual about humor appreciation. It is something you can practice, something you can get better at. At the very least, you now have a scientific reason to watch funny videos on YouTube.”

“Once you start being productive, dopamine is released in the striatum and parts of the prefrontal cortex. Suddenly you’ll have more energy and motivation to do the thing you really need to do.”

“Serotonin helps with impulse control, willpower, and resilience. Dopamine is important in enjoyment and habits. Norepinephrine modulates focus and concentration. Oxytocin is essential to close relationships. Other neurotransmitters are important too, like GABA (antianxiety), endorphins (elation and pain relief), and endocannabinoids (appetite and peacefulness). Other chemicals, like BDNF, help grow new neurons, and even proteins in the immune system play a role.”