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Quote by Kay Redfield Jamison

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An Unquiet Mind: A Memoir of Moods and Madness

This memoir offers an intimate look into the life of a distinguished psychiatrist as they navigate the complexities of bipolar disorder. The author candidly shares their struggles, insights, and triumphs, providing a unique perspective on mental health and the human condition. more

Author

Kay Redfield Jamison
Kay Redfield Jamison

Kay Redfield Jamison is an American psychologist known for her research on mood disorders, particularly bipolar disorder. Her work delves into the relationship between psychological illness and artistic creation, profoundly influencing public understanding of mental health issues. more

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“Lithium regulates the proteins that control the body’s inner clock. This clock runs, oddly, on DNA, inside special neurons deep in the brain. Special proteins attach to people’s DNA each morning, and after a fixed time they degrade and fall off. Sunlight resets the proteins over and over, so they hold on much longer. In fact, the proteins fall off only after darkness falls—at which point the brain should “notice” the bare DNA and stop producing stimulants. This process goes awry in manic-depressives because the proteins, despite the lack of sunlight, remain bound fast to their DNA. Their brains don’t realize they should stop revving. Lithium helps cleave the proteins from DNA so people can wind down. Notice that sunlight still trumps lithium during the day and resets the proteins; it’s only when the sunlight goes away at night that lithium helps DNA shake free. Far from being sunshine in a pill, then, lithium acts as “anti-sunlight.” Neurologically, it undoes sunlight and thereby compresses the circadian clock back to twenty-four hours—preventing both the mania bubble from forming and the Black Tuesday crash into depression.”

“Boundaries define where ‘we’ end and ‘they’ begin, protecting our identity and preventing us from being overwhelmed by the imperatives of others. Properly utilized, silence can be an extraordinarily effective method for establishing and maintaining such boundaries.”

“Once I started seeing the college clinic psychiatrist, he pulled out my blood and showed me what was really in it, glanced at each trace mineral in the lab results, each lurking marker, but his eyes were focused on the good stuff, the chemicals he'd put there. I don't know if I believe in "Indian blood," but at times, I have wished I could test positive for it when the phlebotomist pulled my blood every month, checking to make sure my lithium levels aren't high enough to pickle my kidneys. Instead, the doctor only ever reads off results that sound like the bottom of a deep quarry, as though my body collects stones.”

“Alek didn’t move, unsure what he could say or do to erase her pain. Like the rest of the Draig, he was a warrior, a fighter, used to the action of doing what needed to be done. But in this situation there was no giant fanged yorkin to hunt, no Var army to battle. There was only reality and the flawed nature of imperfect men. - Dragon Lords 6: The Stubborn Lord by Michelle M. Pillow - Coming 2013”

“Who are you? She asked silently, as she laid away the collector's quotations, his drawings, his scraps of famous poetry: "Come live with me and be my love..." interleaved with menus: 'oysters, fish stew, tortoise in its shell, bread from the oven, honey from the honeycomb.' The books were unsplattered but much fingered, their pages soft with turning and re-turning, like collections of old fairy tales. Often Jess thought of Rapunzel and golden apples and enchanted gardens. She thought of Ovid, and Dante, and Cervantes, and the Pre-Raphaelites, for sometimes McClintock pictured his beloved eating, and sometimes sleeping in fields of poppies, and once throned like Persephone, with strawberry vines entwined in her long hair.”