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“Unfortunately, all life on earth - the only life we know - represents, for all its current variety, the results of a single experiment , for every earthly species evolved from the common ancestry of a single origin. We desperately need a repetition of the experiment (several would be better, but let's not be greedy!) in order to make a judgement. Mars represents our first real hope for a second experiment - the sine qua non - for any proper answer for the question of questions.”

“If physics is too difficult for the physicists, the nonphysicist may wonder whether he should try at all to grasp its complexities and ambiguities. It is undeniably an effort, but probably one worth making, for the basic questions are important and the new experimental results are often fascinating. And if the layman runs into serious perplexities, he can be consoled with the thought that the points which baffle him are more than likely the ones for which the professionals have not found satisfactory answers.”

“Poets, if they're genuine, must keep repeating "I don't know." Each poem marks an effort to answer this statement, but as soon as the final period hits the page, the poet begins to hesitate, starts to realize that this particular answer was pure makeshift that's absolutely inadequate to boot. So the poets keep on trying, and sooner or later the consecutive results of their self-dissatisfaction are clipped together with a giant paperclip by literary historians and called their oeuvre.”

“The page of my notebook was filled with many messy integrals, but all of a sudden I saw emerge a formula for counting. I had begun to calculate a quantity on the assumption that the result was a real number, but found instead that, in certain units, all the possible answers would be integers. This meant that areas and volumes cannot take any value, but come in multiples of fixed units.”

“I asked: 'What is the meaning of my life, beyond time, cause, and space?' And I replied to quite another question: 'What is the meaning of my life within time, cause, and space?' With the result that, after long efforts of thought, the answer I reached was: 'None'.”

“When a scientist doesn't know the answer to a problem, he is ignorant. When he has a hunch as to what the result is, he is uncertain. And when he is pretty darn sure of what the result is going to be, he is still in some doubt. We have found it of paramount importance that in order to progress we must recognize our ignorance and leave room for doubt. Scientific knowledge is a body of statements of varying degrees of certainty - some most unsure, some nearly sure, but none absolutely certain.”

“Principles are concepts that can be applied over and over again in similar circumstances as distinct from narrow answers to specific questions. Every game has principles that successful players master to achieve winning results. So does life. Principles are ways of successfully dealing with the laws of nature or the laws of life. Those who understand more of them and understand them well know how to interact with the world more effectively than those who know fewer of them or know them less well.”

“The problem with ideology is if you got an ideology, you already got your mind made up, you know all the answers, and that makes evidence irrelevant and argument a waste of time, so you tend to govern by assertion and attack. The problem with that is that discourages thinking and gives you bad results.”