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Radiology Renaissance : Unleashing Advancements & Queries

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JEET GHOSH

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“Superimposed on the hierarchical framework of defined components of a cell there is another layer. This second layer is highly flexible and can take on an almost infinite variety of forms, like soft and responsive flesh on a bony skeleton. The deep question is whether this higher layer in the construction of cells is itself organized. Are there hierarchies, or at least rules, in the protein-modifying, RNA splicing, gene-regulating processes of a cell? If so, then we have a chance of understanding them. If not, we will never know exactly what a cell will do next. If the detailed chemistry of the cell is simply the outcome of a historical ragbag of ad hoc interactions, then it will be no more predictable than the weather. I do not have an answer to this question. But two features of cells might be relevant. One is a sense of time, or causation - knowledge of the way that things in the real world follow in a certain sequence. The other is integrity, which enables a cell to distinguish between what belongs to itself and what belongs to the outside world.”

Systems Biology
Book:Wetware: A Computer in Every Living Cell
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“When questions arise of possible harmful effects of pesticides, the defenders of the products always try to narrow the scope of the inquiry to their most immediate, direct and measurable consequences and then downplay them, The critics of pesticides, on the other hand, urge that the ecosystem is strongly interconnected, highly variable and vulnerable. Thus debates around environmental impact become debates on the philosophy of nature: are things readily isolated or richly interacting? Is the average behavior of chemicals and organisms an adequate basis for decision making or must we be concerned with the unevenness of the world? Shall we "be realists" and stick to measurable costs and benefits, or shall we concern ourselves with all kinds of consequences of what we do? Gradually we see a confrontation of the world views of mechanistic reductionism and of dialectical materialism.”

BiologyMaterialismEcologyIdealismMarxismDialecticsReductionismDialectical MaterialismSystems Biology
Book:The Dialectical Biologist
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“The need of theory is supported by the eros of the philosopher. It is not the expression of his will to conquer nature. Therefore, the joys of contemplation are "immediate enjoyments," joys that belong intrinsically to contemplation, and they come without further setting of goals or justification to the one receptive to them. They are not tied to social use, neither dependent upon the opinion of others nor gained from the expectation of future glory. The love for the observation of nature, for the observation of the details of the structure in which nature becomes comprehensible, of the order in which nature is articulated, of the spectacle nature provides for one who takes an interest in its objects, who lets its forms, colors, and sounds affect him, this love accords with the love of oneself. Both discourage highfalutin plans to change the world by the transformation of nature. Both impose moderation on the philosopher. He will be especially adequate to his desire to "contribute" something "to this beautiful system" by his conceiving it as a "system" and as "beautiful." The contribution most his own is that he has the whole in view; that he sees things and beings within the horizon of the whole, that he investigates and orders them as parts, that he knows himself as a part and reflects on his relation to the whole or that he poses the question of the whole. But if he wants to keep the question of the whole in view, he may not lose himself. To conceive the "beautiful system," he must devote himself to it in detail and again return to himself. To be able to observe nature, he may not blend into it. Observation requires both proximity and distance.”

WholeNatureBeautyDistanceSystemProximitySystems Biology
Book:On the Happiness of the Philosophic Life: Reflections on Rousseau's "Rêveries" in Two Books
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“An important attribute of metabolites is their close relationship to both the biological states of interest (i.e. disease status) and relevant genomic, transcriptomic, and proteomic variants causally related to the disease state. As such, metabo-profiles can be viewed as an intermediate measure that links pre-disposing genes and environmental exposures to a resulting disease state. Causal metabolites also typically have a stronger relationship (i.e. larger effect size) to the underlying genetics and the disease phenotype. Thus, the integration of metabolomic data into systems biology approaches may provide a missing link between genes and disease states.”

Network MedicineMetabolomics
Book:Network Medicine: Complex Systems in Human Disease and Therapeutics
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“Raul Fernandez-Crespo MD - Specializes In Urology Raul Fernandez-Crespo MD specializes in urology, and in 2007 he attended the Penn State College of Medicine STEP UP Program. His research at the University of Puerto Rico was centered on topics including robotic assisted radical prostatectomy in obese patients. Dr. Fernandez-Crespo received the General Surgery Award from the University of Puerto Rico School of Medicine, and in 2013, he graduated from Ponce School of Medicine and Health Sciences with his MD.”

Raulfernandezcrespomd
Author:Raul Fernandez-Crespo MD
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“Regardless of the delivery method, your Higher Mind will leave you a trail of popcorn. It's been happening all along, even if you've been unaware, trampling it underfoot. It may only be one kernel at a time, but that's all you really need.”

IntuitionManifestingGuidance QuotesBliss QuotesLaw Of Attraction LoveSoul Mates Loves
Book:How I Met the Man of My Dreams: a guide to MANifesting yours
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“I remember reading once how some Stone Age Indians from the Brazilian rain forest with no knowledge or expectation of a world beyond the jungle were taken to Sao Paulo or Rio, and when they saw what it contained-the buildings, the cars, the passing airplanes-and how thoroughly at variance it was with their own simple lives, they wet themselves, lavishly and in unison. I believe I had some idea how they felt. It is such a strange contrast. When you’re on the AT, the forest is your universe, infinite and entire. It is all you experience day after day. Eventually it is about all you can imagine. You are aware, of course, that somewhere over the horizon there are mighty cities, busy factories, crowded freeways, but here in this part of the country, where woods drape the landscape for as far as the eye can see, the forest rules. Even the little towns like Franklin and Hiawassee and even Gatlinburg are just way stations scattered helpfully through the great cosmos of woods. But come off the trail, properly off, and drive somewhere, as we did now, and you realize how magnificently deluded you have been. Here, the mountains and woods were just backdrop-familiar, known, nearby, but no more consequential or noticed than the clouds that scudded across their ridgelines. Here the real business was up close and on top of you: gas stations, Wal-Marts, Kmarts, Dunkin Donuts, Blockbuster Videos, a ceaseless unfolding pageant of commercial hideousness.”

NatureModernityAppalachain Trail
Book:A Walk in the Woods: Rediscovering America on the Appalachian Trail
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