“As with Dalton and the atom, neither Bateson nor Johannsen had any understanding of what a gene was. They could not fathom its material form, its physical or chemical structure, its location within the body or inside the cell, or even its mechanism of action. The word was created to mark a function; it was an abstraction. A gene was defined by what a gene does: it was a carrier of hereditary information. “Language is not only our servant,” Johannsen wrote, “[but] it may also be our master. It is desirable to create new terminology in all cases where new and revised conceptions are being developed. Therefore, I have proposed the word ‘gene.’ The ‘gene’ is nothing but a very applicable little word. It may be useful as an expression for the ‘unit factors’ . . . demonstrated by modern Mendelian researchers.” “The word ‘gene’ is completely free of any hypothesis,” Johannsen remarked. “It expresses only the evident fact that . . . many characteristics of the organism are specified . . . in unique, separate and thereby independent ways.”
Quote by Siddhartha Mukherjee
Work
The Gene: An Intimate History
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