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Quote by Yuval Noah Harari

“If the adoption of ploughing increased a village's population from a hundred to 110, which ten people would have volunteered to starve so that the others could go back to the good old time? There was no going back. The trap snapped shut. The pursuit of an easier life resulted in much hardship, and not for the last time. It happens to us today. How many young college graduates have take demanding jobs in high-powered firms, vowing that they will work hard to earn money that will enable them to retire and pursue their real interests when they are thirty-five? But by the time they reach that age, they have large mortgages, children to school, houses in the suburbs that necessitate at least two cars per family, and a sense that life is not worth living without really good wine and expensive holidays abroad.”

Quote by Yuval Noah Harari

Book:Sapiens: A Brief History of Humankind
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Sapiens: A Brief History of Humankind

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Yuval Noah Harari

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“Superimposed on the hierarchical framework of defined components of a cell there is another layer. This second layer is highly flexible and can take on an almost infinite variety of forms, like soft and responsive flesh on a bony skeleton. The deep question is whether this higher layer in the construction of cells is itself organized. Are there hierarchies, or at least rules, in the protein-modifying, RNA splicing, gene-regulating processes of a cell? If so, then we have a chance of understanding them. If not, we will never know exactly what a cell will do next. If the detailed chemistry of the cell is simply the outcome of a historical ragbag of ad hoc interactions, then it will be no more predictable than the weather. I do not have an answer to this question. But two features of cells might be relevant. One is a sense of time, or causation - knowledge of the way that things in the real world follow in a certain sequence. The other is integrity, which enables a cell to distinguish between what belongs to itself and what belongs to the outside world.”

Systems Biology
Book:Wetware: A Computer in Every Living Cell
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“When questions arise of possible harmful effects of pesticides, the defenders of the products always try to narrow the scope of the inquiry to their most immediate, direct and measurable consequences and then downplay them, The critics of pesticides, on the other hand, urge that the ecosystem is strongly interconnected, highly variable and vulnerable. Thus debates around environmental impact become debates on the philosophy of nature: are things readily isolated or richly interacting? Is the average behavior of chemicals and organisms an adequate basis for decision making or must we be concerned with the unevenness of the world? Shall we "be realists" and stick to measurable costs and benefits, or shall we concern ourselves with all kinds of consequences of what we do? Gradually we see a confrontation of the world views of mechanistic reductionism and of dialectical materialism.”

BiologyMaterialismEcologyIdealismMarxismDialecticsReductionismDialectical MaterialismSystems Biology
Book:The Dialectical Biologist
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Book:On the Happiness of the Philosophic Life: Reflections on Rousseau's "Rêveries" in Two Books
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“An important attribute of metabolites is their close relationship to both the biological states of interest (i.e. disease status) and relevant genomic, transcriptomic, and proteomic variants causally related to the disease state. As such, metabo-profiles can be viewed as an intermediate measure that links pre-disposing genes and environmental exposures to a resulting disease state. Causal metabolites also typically have a stronger relationship (i.e. larger effect size) to the underlying genetics and the disease phenotype. Thus, the integration of metabolomic data into systems biology approaches may provide a missing link between genes and disease states.”

Network MedicineMetabolomics
Book:Network Medicine: Complex Systems in Human Disease and Therapeutics
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“Raul Fernandez-Crespo MD - Specializes In Urology Raul Fernandez-Crespo MD specializes in urology, and in 2007 he attended the Penn State College of Medicine STEP UP Program. His research at the University of Puerto Rico was centered on topics including robotic assisted radical prostatectomy in obese patients. Dr. Fernandez-Crespo received the General Surgery Award from the University of Puerto Rico School of Medicine, and in 2013, he graduated from Ponce School of Medicine and Health Sciences with his MD.”

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