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“It's really hard to design products by focus groups. A lot of times, people don't know what they want until you show it to them. As Henry Ford said many years earlier: "If I had listened to my customers, I would have built a faster horse." Inventions in general express Shannon entropy. They come from the supply side.”

“Money is not an invention of the state. It is not the product of a legislative act. Even the sanction of political authority is not necessary for its existence. Certain commodities came to be money quite naturally, as the result of economic relationships that were independent of the power of the state.”

“The inhabitant of London could order by telephone, sipping his morning tea in bed, the various products of the whole earth -- he could at the same time and by the same means adventure his wealth in the natural resources and new enterprise of any quarter of the world -- he could secure forthwith, if he wished, cheap and comfortable means of transit to any country or climate without passport or other formality.”

“Getting a traditional pharmaceutical to the market can cost a billion dollars or more. Newer, more tailored and targeted drugs called biologics are even more complex and expensive. Simple economics dictates that companies and venture funds will invest more in products that can generate a sufficient return.”