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“When Franklin drew the lightning from the clouds, he little dreamed that in the evolution of science his discovery would illuminate the torch of Liberty for France and America. The rays from this beacon, lighting this gateway to the continent, will welcome the poor and the persecuted with the hope and promise of homes and citizenship.”

“In physiology, as in all other sciences, no discovery is useless, no curiosity misplaced or too ambitious, and we may be certain that every advance achieved in the quest of pure knowledge will sooner or later play its part in the service of man.”

“The Dark Ages may return-the Stone Age may return on the gleaming wings of Science; and what might now shower immeasureable material blessings upon mankind may even bring about its total destruction. Beware! I say. Time may be short. Referring to the discovery of atomic energy.”

“Today, nothing is unusual about a scientific discovery's being followed soon after by a technical application: The discovery of electrons led to electronics; fission led to nuclear energy. But before the 1880's, science played almost no role in the advances of technology. For example, James Watt developed the first efficient steam engine long before science established the equivalence between mechanical heat and energy.”

“In the world's history certain inventions and discoveries occurred, of peculiar value, on account of their great efficiency in facilitating all other inventions and discoveries. Of these were the art of writing and of printing - the discovery of America, and the introduction of Patent-laws. The date of the first ... is unknown; but it certainly was as much as fifteen hundred years before the Christian era; the second-printing-came in 1436, or nearly three thousand years after the first. The others followed more rapidly - the discovery of America in 1492, and the first patent laws in 1624.”

“Science is a human activity, and the best way to understand it is to understand the individual human beings who practise it. Science is an art form and not a philosophical method. The great advances in science usually result from new tools rather than from new doctrines. ... Every time we introduce a new tool, it always leads to new and unexpected discoveries, because Nature's imagination is richer than ours.”

“What struck me most in England was the perception that only those works which have a practical tendency awake attention and command respect, while the purely scientific, which possess far greater merit are almost unknown. And yet the latter are the proper source from which the others flow. Practice alone can never lead to the discovery of a truth or a principle. In Germany it is quite the contrary. Here in the eyes of scientific men no value, or at least but a trifling one, is placed upon the practical results. The enrichment of science is alone considered worthy attention.”

“There was, I think, a feeling that the best science was that done in the simplest way. In experimental work, as in mathematics, there was "style" and a result obtained with simple equipment was more elegant than one obtained with complicated apparatus, just as a mathematical proof derived neatly was better than one involving laborious calculations. Rutherford's first disintegration experiment, and Chadwick's discovery of the neutron had a "style" that is different from that of experiments made with giant accelerators.”

“There is something in such laws that takes the breath away. They are not discoveries or inventions of the human mind, but exist independently of us. In a moment of clarity, one can at most discover that they are there and take them into account. Long before there were people on the earth, crystals were already growing in the earth's crust. On one day or another, a human being first came across such a sparkling morsel of regularity lying on the ground or hit one with his stone tool and it broke off and fell at his feet, and he picked it up and regarded it in his open hand, and he was amazed.”