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“Most of us stand poised at the edge of brilliance, haunted by the knowledge of our proximity, yet still demonstrably on the wrong side of the line, our dealings with reality undermined by a range of minor yet critical psychological flaws (a little too much optimism, an unprocessed rebelliousness, a fatal impatience or sentimentality). We are like an exquisite high-speed aircraft which for lack of a tiny part is left stranded beside the runway, rendered slower than a tractor or bicycle.”

“If I tell you my character has grey hair, you will not see her. If I tell you she has a tiny scar at the upper left corner of her lip from which protrudes one grey whisker—you will make up the rest of her face with absolute clarity. If I tell you my character is waiting in a car, you won’t be ‘caught,’ but if I tell you he pushes his fingers down in the crack of the car seat where the ancient leather has pulled away from the seat frame, and pulls up a small coin purse with a faded note in it—you will be mine.”

“How ignorant we are! How ignorant everyone is! We can cut across only a small area of the appallingly expanding fields of knowledge. No human being can know more than a tiny fraction of the whole. It must have been satisfactory in ancient times when one's own land seemed to be the universe; when research studies, pamphlets, books did not issue in endless flow; when laboratories and scientists were not so rapidly pushing back frontiers of knowledge that the process of unlearning the old left you gasping for breath.”

“Sherlock Holmes took his bottle from the corner of the mantel-piece, and his hypodermic syringe from its neat morocco case. With his long, white, nervous fingers he adjusted the delicate needle, and rolled back his left shirt-cuff. For some little time his eyes rested thoughtfully upon the sinewy forearm and wrist, all dotted and scarred with innumerable puncture-marks. Finally, he thrust the sharp point home, pressed down the tiny piston, and sank back into the velvet-lined armchair with a long sigh of satisfaction.”