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“Stupidity is a factor to be reckoned with in human affairs. The true leader always expects to encounter it, and prepares to endure it patiently so long as it is normal stupidity. He knows that his ideas will be distorted, his orders carelessly executed; and that there will be jealousy among his assistants. He takes these inevitable phenomena into account, and instead of attempting to find men without faults, who are non-existent, he tries to make use of the best men at his disposal - as they are, and not as they ought to be.”

“It is my greatest misfortune to be too lazy, and by the few mortifications I have already set with on that account I predict many evils in my future life. I have always the inclination to do what I ought; but by continually procrastinating for tomorrow the business of today, I insensibly delay, until at the end of one month I find myself in the same place as when I began it.”

“The first business of philosophy is to account for things as they are; and till our theories will do this, they ought not to be the ground of any practical conclusion.”

“Sacred interpreter of human thought, How few respect or use thee as they ought! But all shall give account of every wrong, Who dare dishonor or defile the tongue; Who prostitute it in the cause of vice, Or sell their glory at a market-price!”

“Our friends should be our incentives to right, but not only our guiding, but our prophetic, stars. To love by right is much, to love by faith is more; both are the entire love, without which heart, mind, and soul cannot be alike satisfied. We love and ought to love one another, not merely for the absolute worth of each, but on account of a mutual fitness of temporary character.”

“When you set about your composing, it may be necessary for your ease, and better distillation of wit, to put on your worst clothes, and the worse the better; for an author, like a limbeck, will yield the better for having a rag about him: besides that, I have observed a gardener cut the outward rind of a tree (which is the surtout of it) to make it bear well; and this is a natural account of the usual poverty of poets, and is an argument why wits, of all men living, ought to be ill clad.”

“I mean to say, I know perfectly well that I've got, roughly speaking, half the amount of brain a normal bloke ought to possess. And when a girl comes along who has about twice the regular allowance, she too often makes a bee line for me with the love light in her eyes. I don't know how to account for it, but it is so." "It may be Nature's provision for maintaining the balance of the species, sir.”

“If the account given in Genesis is really true, ought we not, after all, to thank this serpent? He was the first schoolmaster, the first advocate of learning, the first enemy of ignorance, the first to whisper in human ears the sacred word liberty, the creator of ambition, the author of modesty, of inquiry, of doubt, of investigation, of progress and of civilization.”

“A year ago Guyana became politically free and independent. She assumed the untrammeled right to make her own decisions on what ought to be done or ought not to be done within her border. Since then, hers has also been the right to decide what course she would take and to state her views and opinions positively in the fora of the world. As we celebrate the first anniversary of freedom, it is our duty to take account of what we have achieved or what we have failed to do, to note where we have done well and what we ought to have done better.”

“In order that the relations between science and the age may be what they ought to be, the world at large must be made to feel that science is, in the fullest sense, a ministry of good to all, not the private possession and luxury of a few, that it is the best expression of human intelligence and not the abracadabra of a school, that it is a guiding light and not a dazzling fog.”

“It is the very strangeness of nature that makes science engrossing. That ought to be at the center of science teaching. There are more than seven-times-seven types of ambiguity in science, awaiting analysis. The poetry of Wallace Stevens is crystal-clear alongside the genetic code.”

“It is unreasonable to expect science to produce a system of ethics-ethics are a kind of highway code for traffic among mankind-and the fact that in physics atoms which were yesterday assumed to be square are now assumed to be round is exploited with unjustified tendentiousness by all who are hungry for faith; so long as physics extends our dominion over nature, these changes ought to be a matter of complete indifference to you.”

“The more experiences and experiments accumulate in the exploration of nature, the more precarious the theories become. But it is not always good to discard them immediately on this account. For every hypothesis which once was sound was useful for thinking of previous phenomena in the proper interrelations and for keeping them in context. We ought to set down contradictory experiences separately, until enough have accumulated to make building a new structure worthwhile.”

“If the question were, "What ought to be the next objective in science?" my answer would be the teaching of science to the young, so that when the whole population grew up there would be a far more general background of common sense, based on a knowledge of the real meaning of the scientific method of discovering truth.”