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“The problem is that for almost any feature of humanity that you can name, whether it's the ability to suffer, whether it's the capacity to reason, whether it's having lives that can go better or worse, there are at least some other non-human animals that have all of these features as well. So to exclude non-human animals from the range of moral concern but to include all humans, just seems morally arbitrary.”

“I think the mother of all arguments against eating meat now is the climate change argument. Methane is a much more powerful greenhouse gas than carbon dioxide and when we eat meat we wipe away many of the good things that we do when we try to create greener and more sustainable practices in the rest of our lives. So if you add the concern for climate change with other concerns that were there. I think the case for vegetarianism is pretty overwhelming.”

“None of us are rational economic men as we're supposed to be portrayed in economic theory where mixes of passions, of desires, of moral principles, of self-deception, of altruism, of concern of others, of concerns for ourselves and an interest in our bank accounts. And social policies have to be responsive to the complexity of who we are as people or else, like the war on drugs, they're simply going to fail.”

“There's going to be biological differences between the genders. There's going to be biological differences between two women or two men. There's biological differences between all of us. My concern is, why are we so concerned about it? Why are we so worried about it? Why, whenever a study comes out about men do this one way and women do this one way, or men's brains and women's brains - why are we so interested in that? You know, what makes us so fascinated by differences between the sexes? And I think more often than not that interest is deeply embedded in sexism.”

“One of the biggest concerns about going out beyond lower Earth orbit is the radiation. We find that exercise seems to counteract a lot of the negative effects of space flight, like bone loss and muscle atrophy and cardiovascular systems issues. We exercise two hours a day on the station, which is a huge hit out of your day. It's great for staying in shape, but you know, it cuts into the productivity of the crew and if you look at how expensive it is to get a crew into space, if we can keep them healthy and have them exercise, but spend less time doing it, we can get more done.”

“All sorts of things can keep one awake. But as you get older - this is what the stroke thing really brought home to me - this thing that I never paid attention to: my brain. I've always been conscious that, of course, after a night of getting stoned, my head would feel foggy; if I got drunk the night before I'd be hungover. But that was the extent of my concern about my brain. And then with the stroke thing, it made me realize, "God! That's my main source of income." So it relates actually to your other question about growing old.”

“You cannot overestimate the role of intuition in fiction writing. Or the role of accident or randomness. These things are very central. This is never really admitted. You have to cover the pages. You have to have those people do things. And the things they do have to be relevant to the entire concern. The specific things they do don't much matter, you just have to have them do something that counts.”

“I have a fairly unwieldy set of concerns that go into determining what I do in the paintings, such as the history of the decorative, patterns of cultural migration, Islamic art and design, Byzantine architecture, the annals of natural history, as well as contemporary painting. All of these things are filtered through my own sense of cultural urgency. How I proceed with the work has to do with how I respond to this instinctively chosen mass of materials. I'm weighing many things and making many decisions before I even get started on a painting.”

“Living in Portland, which is a predominantly white city, the privilege and the luxury to be able to obsess over a certain kind of minutia, that I think, if you did not have that privilege, would never be bothersome. When people are worried about whether "local" means 100 miles, or 50 miles, or 10 miles from a grocery store, I just think, "Wow. What a privilege it is to have that as a major concern in your life." As opposed to, "Can we afford food tonight?" Sometimes I'm just shocked at what becomes concerning in these kind of communities.”

“Fifteen years after the new dispensations started in South Africa, if one looks back, there are reasons to be positive and say we have achieved what we wanted to achieve, but there are also reasons for concern. Not everything turned out exactly as I would have liked it to turn out. On the positive side, we have a good constitution, there has been no effort to really amend the constitution and change the values and the principles contained therein and in our bill of rights.”

“I do know that the effect of the tremendous cutbacks on education that we're seeing are going to create a major problem for the country if we don't provide the opportunity to a huge swath of our society. These impacts are going to have an effect across national security, it's going to have an effect across our social services, and of course on the economy, in broad terms. So there is, I think, at least a level of concern that we ought to have at this point in our history.”

“The Republicans had their shot not long ago to address the real needs and concerns of everyday Americans, and they blew it. I think that's mitigated by the fact that we had a terrorist incident, there is a war, and there was a lot of proper focus on those issues, but over the time that they were there and had the leadership opportunity, they blew it. We got fired for a reason.”

“It was assumed that you can't touch evangelical Christians. "Oh, they're the Republican Right. Stay away from those people. Don't even try to talk to them." Well, what's interesting is that there were evangelical Christians who were voting for Kerry. There were right-to-lifers who were voting for Kerry. And it's interesting to listen to the reasons why. To ignore that segment of the electorate is moronic. Particularly if you don't know who those people are, or what their concerns are.”

“There is age discrimination, but I think there are two kinds. One is when the employer is discriminating for specific reasons and doing it intentionally. The other is where you have managers who really aren't looking to discriminate but feel a little on edge because the candidate they're talking to is older. Sometimes they can even smell age concern on the part of the candidate and they wind up discriminating almost unconsciously.”

“I think the most important thing is the American people have lost trust and confidence in the people they have sent up to Congress as elected leaders. And I think that it is so important to reconnect to the people. And I think that the last election showed people weren't running back to the Republican Party. They did show that they weren't happy with the policies coming out of the Democrat Party. But they are trying to find individuals that will go up and be their voice, that will resemble them, that will take their cares and concerns to Washington, D.C.”

“Change can only come from local citizens and politicians - it cannot be imposed by well-meaning foreigners - not least because a society like Afghanistan or Iraq is suspicious of outsiders and often resistant to change. I am not going to get drawn into the ethics of intervening in other countries. My concern is the practical question. Can you actually achieve change in this way? My guess is we can stop wars sometimes as in the Balkans and topple regimes - but that the other stuff - such as corruption is not within our power to effect and alter.”

“Unfortunately, some of the young talants are becoming fashionable. And anything that's fashionable can become unfashionable. So one has to watch that. And it's very easy today because there are so many events - art fairs, gallery openings, etcetera. In fact, that's another thing that concerns me, the quantity of gallery openings. In my office in London, I get back after a week, and I have 30 invitations. It's too much.”

“When philosophers talk about reason they often have in mind Having been in the business of philosophy more than half my life, I have learned that reason doesn't change many minds. But there's a more ordinary sense of resonableness, which involves not just logic but a sensitivity to other peoples real concerns, a desire to understand, even when you don't agree. Many people are reasonable in this way.I'm willing to think that the world will be made better by the conversations of reasonable people, even if there are unreasonable people and people who don't want to converse as well.”

“The real concern is that Iran would do what Pakistan did. Pakistan wanted nuclear weapons, like Iran, purely for defensive reasons - to defend itself against India. The problem was that once Pakistan acquired the weapons, it allowed the country to be more aggressive. So they stepped up their support for the Kashmiri terrorists, and it led very quickly to the Kargil crisis in 2000, which almost sparked a nuclear war between India and Pakistan.”

“The policy that received more attention particularly in the past decade and a half or so has been the US cocaine policy, the differential treatment of crack versus powder cocaine and question is how my research impacted my view on policy. Clearly that policy is not based on the weight of the scientific evidence. That is when the policy was implemented, the concern about crack cocaine was so great that something had to be done and congress acted in the only way they knew how, they passed policy and that's what a responsible society should do.”

“Crack in the early 1980s or mid 1980s I'm sorry is that one of the worst myth is that one hit and you're addicted for life. We saw that in 1980s and we're seeing it again with methamphetamine today, one hit and you're addicted and it simply not true, addiction requires work not the people should go out and experiment or do these themselves but the fact is that's a myth and the concern is that, it's dangerous because when people perpetuates that myths and then when young people are people actually try methamphetamine or crack cocaine and find that, that doesn't happen to them.”

“Many environmentalists have failed to recognize that the preservation of quiet areas, places off-limits to noise pollution, should probably be a number-one environmental concern, not something we're going to get to later. And I say that because in that quiet is a whole experience that people can have that reaches to their soul. I like to think of quiet places in nature as the think tank of the soul. It's in these very basic levels that we'll be able to see what the real problem is.”