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“There is a safe, nontoxic drug called naloxone that can instantly reverse opioid overdose and prevent most of these deaths. But the drug war interferes with saving overdose victims in two ways: first, because witnesses to overdose fear prosecution, they often don't call for help until it's too late. Second, because the drug war supports the belief that making naloxone available over-the-counter or with opioid prescriptions would encourage drug use, the antidote is available only through harm reduction programs like needle exchanges or in some state programs aimed at drug users.”

“Of course all life is a process of breaking down, but the blows that do the dramatic side of the work-- the big sudden blows that come, or seem to come, from outside-- the ones you remember and blame things on and, in moments of weakness, tell your friends about, don't show their effect all at once. There is another sort of blow that comes from within-that you don't feel until it's too late to do anything about it, until you realize with finality that in some regard you will never be as good a man again.”

“Nobody's good. I hate it. I truly hate it. I mean, there's a lot of guys doing stuff I admire, but stand-up-wise I feel very alone. I really miss Bill Hicks. I wish I could have put him on my show. And I really miss Sam Kinison a lot. Richard Pryor's sick... It's like you get here and then, oh wait a minute, there's nobody here any more. I feel like the guy who finally got into Studio 54, three years too late, Duh, where are all the famous people?”

“A prayerful life is the key to possessing gratitude. We often take for granted the people who most deserve our gratitude. Let us not wait until it is too late for us to express our gratitude. Feeling gratitude and not expressing it is like wrapping a present and not giving it. If I gratitude be numbered among the serious sins, then gratitude takes its place among the noblest of virtues. To express gratitude is gracious and honorable, to enact gratitude is generous and noble, but to live with gratitude ever in our hearts is to touch heaven.”

“I'm not saying this because I'm looking for a soft cushion wherever I'm heading, I just feel that I've got thousands and thousands of young fans that have to learn about what's real when it comes to AIDS. Like the others before me, I would like to turn my own problem into something good that will reach out to all my homeboys and their kin. Because I want to save their asses before it's too late.”

“The story of Judith. But one of the reasons I'm doing it is because the roles I've been writing for myself over the past few years have gotten older and older. And I thought, You know, before it's too late, I want to play a sexy, tough young gal again. And I always wanted to do a Biblical epic. So, I'll play a beautiful young widow who saves her people from the Assyrians.”

“I'm often quite gloomy about the prospects for the human future. But, although I have no competence to intervene directly in a political movement, I hope that what I write may, in combination with the suggestions of others, cause a shift in perspective that will inspire a world-wide movement to accept the only solution to climate change. And before it's too late.”

“There's always a question when you invest. Are you too early, are you too late, or are you just right? And there was a lot of hype about life sciences, around the sequencing of the human genome and a lot of people concluded that's not really there. But by the way, there was a lot of hype around the digital revolution just about the time of 2000 and the human genome, and it turns out that some of the world's biggest, most powerful companies are the survivors post that crash.”