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“It is imperfection - not perfection - that is the end result of the program written into that formidably complex engine that is the human brain, and of the influences exerted upon us by the environment and whoever takes care of us during the long years of our physical, psychological and intellectual development.”

“I really just drew off of where we are now, with reality TV. You can't help but see a lot of it. You choose to watch some, but with some, you just can't help but hear it and see it. It's just piercing in your brain. That piercing is what I was tapping into , with whatever they were doing to pierce into the minds of everybody. It takes a certain kind of person to shut your mind off to the consequences and just try to get results. That's what I was going for - results.”

“I have been diagnosed with Amyotrophic Lateral Sclerosis (ALS). It's a terminal disease with an average lifespan of two to five years post-diagnosis, and scientists don't know what causes it. ALS prevents your brain from talking to your muscles. As a result, muscles die. As a result, every 90 minutes people die. I am a person.”

“I view all art as an effort to translate brain concepts into a work. These brain concepts are synthetic ones - the result of many experiences. But a single work of art, or even a series of works, more often than not cannot translate these synthetic concepts adequately. Yves Saint Laurent once said that he suffered greatly when creating. He is not alone in that. Most artists do the same and say as much.”

“The objective psychologist, hoping to get at the physiological side of behavior, is apt to plunge immediately into neurology trying to correlate brain activity with modes of experience ... The result in many cases only accentuates the gap between the total experience as studied by the psychologist and neural activity as analyzed by the neurologist.”

“I believe C++ instills fear in programmers, fear that the interaction of some details causes unpredictable results. Its unmanageable complexity has spawned more fear-preventing tools than any other language, but the solution should have been to create and use a language that does not overload the whole goddamn human brain with irrelevant details.”

“London always reminds me of a brain. It is similarly convoluted and circuitous. A lot of cities, especially American ones like New York and Chicago, are laid out in straight lines. Like the circuits on computer chips, there are a lot of right angles in cities like this. But London is a glorious mess. It evolved from a score or so of distinct villages, that merged and meshed as their boundaries enlarged. As a result, London is a labyrinth, full of turnings and twistings just like a brain.”

“When something like this happens, you suddenly have no sense of reality at all. You have lost a piece of your past. The infidelity itself is small potatoes compared to the low-level brain damage that results when a whole chunk of your life turns out to have been completely different from what you thought it was. It becomes impossible to look back at anything that's happened ... without wondering what was really going on.”

“The war between authors and publishers has been a conflict of ages. On the one side, the publisher has been looked upon as a species of Wantley dragon, whose daily food was the brain and blood of hapless writers. ... On the other side, the author has been considered, like Shelley, 'an eternal child,' in all that relates to practical matters, and a terrible child at that, - incapable of comprehending details, and unreasoanably dissatisfied with results.”

“The culture and educational system of the contemporary West are based almost exclusively upon the training of the reasoning brain and, to a lesser degree, of the aesthetic emotions. Most of us have forgotten that we are not only brain and will, senses and feelings; we are also spirit. Modern man has for the most part lost touch with the truest and highest aspect of himself; and the result of this inward alienation can be seen all too plainly in his restlessness, his lack of identity and his loss of hope.”

“A young financial writer once brought ridicule upon himself by stating that a certain company had nothing to commend it except excellent earnings. Well, there are companies whose earnings are excellent but whose stocks I would never recommend. In selecting investments, I attach prime importance to the men behind them. I'd rather buy brains and character than earnings. Earnings can be good one year and poor the next. But if you put your money into securities run by men combining conspicuous brains and unimpeachable character, the likelihood is that the financial results will prove satisfactory.”