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“Sometimes all that saves me is being willing to make mistakes. There are projects that strike me as so beautiful, important, complicated, or just plain big, that they convince me of my own inadequacy. This awful state of reverence leads to paralyzing brain freeze. At times like that the only way out is for me to decide, 'To hell with it. I can't do it right, so I'll do it wrong. I can't do it well, but I can do it badly.' Sometimes, with luck, while I'm sweating to do it wrong, I stumble on a right way.”

“It's the old idea that the process of evolution is some push in the direction of greater complexity--in particular greater intellectual complexity. In one twig of the tree of life, namely ours, having a big brain happened to have advantages. But that's just what worked for a particular species of primate 5 to 7 million years ago.”

“About the book of Job: If it were today, God might be asking "How does DNA carry traits? How are instincts passed on in animals? How does consciousness arise in the human body and brain, and what is consciousness? What is dark matter? How did the big bang happen? Why does the speed of light appear to be absolute? Is cold fusion possible? How do you program a TV remote control?”

“Dinosaurs were huge and powerful; they could not adapt and they died out. And so the big difference between dinosaurs and cockroaches is adaptability: one is able to adjust, while the other, apparently, couldn't... The same analogy applies to fighting, and probably any other sport. It's not always the strong that survive. It takes brains, guts, tolerance and forward thinking. We've seen this since the beginning of mixed martial arts.”

“Does religion fill a much needed gap? It is often said that there is a God-shaped gap in the brain which needs to be filled: we have a psychological need for God -- imaginary friend, father, big brother, confessor, confidant -- and the need has to be satisfied whether God really exists or not. But could it be that God clutters up a gap that we'd be better off filling with something else? Science, perhaps? Art? Human friendship? Humanism? Love of this life in the real world, giving no credence to other lives beyond the grave?”

“Wrangham cites several studies indicating that in fact humans don't do well on raw food: they can't maintain their body weight, and half of the women on a raw-food regimen stop menstruating. Devotees of raw food rely heavily on juicers and blenders, because otherwise they would have to spend as much time chewing as the chimps do. It is difficult, if not impossible, to extract sufficient energy from unprocessed plant matter to power a body with such a big, hungry brain.”

“But the Fear (that sensation that all writers get of how the hell do words get from my puny little brain to into a book, and isn't magic somehow involved, and surely I'm not qualified to be involved in any part of that process, and I somehow managed that tomorrow, but you mean I have to do it this morning too, well how do I even start?) withdraws quite a bit when it's already light and lovely outside when I get to my desk. So I got right past that big moment today, and into the fun slide down towards the ending, yelling whee.”

“I was never very good at math and science, to be honest, so it's fun to play a character that is so scientific and mathematical, and whose brain functions at such a high pace. The biggest difference is that Maura is very linear in her thinking and very logical. I'm not quite like that. I'm much more laid back and not quite so type A. That's the big difference.”

“Statistically, I'd say comedy writers are perhaps the sanest category of show people. And why not? They make big money, and although it's not an easy trade - particularly when you're at your galley oar five days a week - it's easier on the nerves and the psyche than living with the brain-squeezing pressure and cares of being the Star.”

“I think of this a lot in the terms of books. Of course there's a big to-do culturally about e-books versus print books, sales models. The paradigm has changed but my perspective on it is that there's not going to be another paradigm to alight on because everything will continue to evolve so quickly that our brains won't be able to keep up with it.”

“The radical is simply being given more room in the mainstream. And I think young people - I'm talking about the very young millennials - they are bored by so much so fast and have such fast big brains, that they won't digest lazy uninteresting work in the way my generation might have. This is a great opportunity for those on the fringe to be less on the fringe perhaps.”