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“Personally, I’ve gotten so that I now use a kind of two-track analysis. First, what are the factors that really govern the interests involved, rationally considered? And second, what are the subconscious influences where the brain at a subconscious level is automatically conclusions in various ways — which, by and large, are useful — but which often malfunction? One approach is rationality… And the other is to evaluate the psychological factors that cause subconscious conclusions — many of which are wrong.”

“Sometimes all that saves me is being willing to make mistakes. There are projects that strike me as so beautiful, important, complicated, or just plain big, that they convince me of my own inadequacy. This awful state of reverence leads to paralyzing brain freeze. At times like that the only way out is for me to decide, 'To hell with it. I can't do it right, so I'll do it wrong. I can't do it well, but I can do it badly.' Sometimes, with luck, while I'm sweating to do it wrong, I stumble on a right way.”

“For me, I was in school and I pushed myself to be a good student, just because that's the type of person I was, but I never had a connection to any of it. I don't think my brain functioned in a way that was at its height, when I was in school. I needed something like art to really value the way my mind works. I wasn't reaching my full potential by sitting in a classroom and reading from a book. My mind didn't work that way.”

“Slyly, banteringly, but also overbearingly, the critic - the one who does not swallow anything whole, who waits until posterity has consecrated it before... howling - is among those who howl their admiration the way they howl their insults: don't be afraid, don't tremble - the beast doesn't have any nails or teeth, or even brain: it is stuffed.”

“Diatonic, he heard the word in his head. Chromatic, pentatonic, hexatonic, heptatonic, octatonic, each iteration of the scale opening innumerable possibilities for harmony. He thought about the Pythagorean major third, the Didymus comma, the way the intervals sound out of tune rather than as though they were different notes. This, he thought, was where his brilliance at mathematics bled into his love of music; music was the realm in which his mathematical brain danced.”

“Ninety percent of our lives is governed by emotion. Our brains merely register and act upon what is telegraphed to them by our bodily experience. Intellect is to emotion as our clothes are to our bodies; we could not very well have civilized life without clothes, but we would be in a poor way if we had only clothes without bodies.”

“The computer has evolved into a partner, a tool, and an environment--not just in science fiction, but in the public consciousness as well. Computers are no longer malevolent iron brains that manufacture tyrannical and oppressive answers; they are not a way to think, they are a place from which to think. The computer is an environment in which answers can be sought, created, manipulated and developed.”

“Greetings, conversationalists across the fruited plain, this is Rush Limbaugh, the most dangerous man in America, with the largest hypothalamus in North America, serving humanity simply by opening my mouth, destined for my own wing in the Museum of Broadcasting, executing everything I do flawlessly with zero mistakes, doing this show with half my brain tied behind my back just to make it fair because I have talent on loan from ... God. Rush Limbaugh. A man. A legend. A way of life.”

“You don’t seduce in the same way at my age. You seduce with brains, with talent. Yesterday for lunch I met the most incredible 90-year-old woman. She survived Auschwitz, she was beautiful, she didn’t have white hair, she didn’t wear glasses. She was totally seductive. I just thought, Oh, my God, I still have time ahead of me.”

“The Sketchnote Handbook is neither about sketching nor is it about note taking. It's about receiving and processing the world in a more complete and insightful way. It's a software upgrade for your brain. For those who've been shamed into thinking that drawing is either beyond them or beneath them, this book offers a whole new way of mastering the daily onslaught of information and turning it into raw material for discovery. (For those of us who've done this all our lives, the book provides a beautifully conceived and lovingly illustrated treat, and a great gift for our left-brained friends.)”

“A meme (rhymes with dream) is a unit of information (a catchphrase, a concept, a tune, a notion of fashion, philosophy or politics) that leaps from brain to brain. Memes compete with one another for replication, and are passed down through a population much the same way genes pass through a species. Potent memes can change minds, alter behavior, catalyze collective mindshifts and transform cultures. Which is why meme warfare has become the geopolitical battle of our information age. Whoever has the memes has the power.”

“The variety of minds served the economy of nature in many ways. The Creator, who designed the human brain for activity, had insured the restlessness of all minds by enabling no single one to envisage all the qualities of the creation. Since no one by himself could aspire to a serene knowledge of the whole truth, all men had been drawn into an active, exploratory and cooperative attitude.”

“We accepted a definition of ourselves which confined the self to the source and to the limitations of conscious attention. This definition is miserably insufficient, for in fact we know how to grow brains and eyes, ears and fingers, hearts and bones, in just the same way that we know how to walk and breathe, talk and think - only we can't put it into words. Words are too slow and too clumsy for describing such things, and conscious attention is too narrow for keeping track of all their details.”

“After directing awhile, you get an instinct about it, but you have to be able to trust your own feelings. Invariably, two-thirds of the way through a film, you say, "Jeezus, is this a pile of crap! What did I ever see in it in the first place?" You have to shut off your brain and forge ahead, because by that time you're getting so brainwashed. Once I commit myself to a film I commit myself to that ending, whatever the motivations and conclusions are.”

“To fire a bullet into the heart or brains of one's fellow man even a fellow man striving to do the same to you creates what might be called an unassimilable memory: a memory that floats on daily life the way an oil stain floats on rainwater. Stir the rain barrel, scatter the oil into countless drops, disperse it all you like, but it will not mix; and eventually the slick comes back, as loathsomely intact as it ever was.”

“You know, not every good book needs to be a movie, or a television series, or a video game. There's great work in those mediums, of course, but sometimes a book should remain a book. I still believe nothing tells a story with the richness and complexity of a good novel. When people say they think a book would make a good movie, they say this sometimes because, if it worked, they already saw all the images in the movie theatre that is in their brains. And sometimes that is the way it should stay.”

“There are so many kinds of madness, so many ways in which the human brain may go wrong; and so often it happens that what we call madness is both reasonable and just. It is so. Yes. A little reason is good for us, a little more makes wise men of some of us--but when our reason over-grows us and we reach too far, something breaks and we go insane.”

“Just as important as getting enough sleep is thinking about sleep in the right way. Stop thinking of sleep and naps as “downtime” or as a “waste of time.” Think of them as opportunities for memory consolidation and enhancing the brain circuits that help skill learning. Nor should you feel guilty about sleep. It's just as crucial a part of successful brain work as the actual task itself.”

“Television is a constant stream of fact, opinions, lies, moral dilemmas, plots: an infinitely complex and sophisticated torrent of information. How could it not make you cleverer? The only people who ever thought television rotted the brain and made kids dumb were those with a vested interest in other ways of learning, or those who were intellectually insecure, usually about books.”

“You are thinking about where your brain is at any time. It's very tricky but it's why women are very well suited to rule the world in the future, because of the multi-tasking they do and their ability to be moving in 15 directions at once. It's the women who behave like men, who focus in that singular way with the blinkers on, who have problems. You get a lot more done that way maybe, but you also lose the perception of who's behind you, what's going on, the 360 degrees of it, the whole picture of life that we do have as women.”

“Sometimes I forget what I put in. I want to capture things in that way, where you're looking into your memory, a dream or hallucination. The characters become a mixture of archetypes, [and] that's what I like. You're trying to figure it out and your brain wants to categorize things, but it can't because of this motion. You want to solve the problem, but it never gets solved. It's like when you read a really good book and the story never leaves you.”

“Think about the way you go surfing on the Internet - you go from one thing to another. You can't really concentrate. I can't sit and read 10 pages on my computer. You'll read and then all of a sudden part of your brain is like, "What about that? ...You're not reading the whole book. You're reading fragments. Even though I think it's bad, I think it's interesting too, because that's the way my brain works.”

“It's the best gift in the world to be able to get up and dance because it's the best gym. You artistically stretch your brain and you physically stretch your body to a higher point than a singular rotation movement like running. It makes your whole body move in lots of different ways, and it can make you very flexible as well, which is good for later life.”

“When you're designing and inventing the way I did, every minute of your life is put - every neuron in your brain into trying to think about the little code and how you can maybe have one less line of code and a little bit more straightforward from the beginning to the answer. And you don't have time to think about companies and products and how would I build this. So Steve Jobs and I were a very necessary pair.”

“True wisdom, indeed, springs from the wide brain which is fed from the deep heart; and it is only when age warms its withering conceptions at the memory of its youthful fire, when it makes experience serve aspiration, and knowledge illumine the difficult paths through which thoughts thread their way into facts,--it is only then that age becomes broadly and nobly wise.”

“No substance in nature, as far as yet known, has, when it reaches the brain, such power to induce mental and moral changes of a disastrous character as alcohol. Its transforming power is marvelous, and often appalling. It seems to open a way of entrance into the soul for all classes of foolish, insane or malignant spirits, who, so long as it remains in contact with the brain, are able to hold possession.”

“[On the Internet and activism:] The danger of the Internet is cocooning with the like-minded online - of sending an email or twitter and confusing that with action - while the real corporate and military and government centers of power go right on. In a way, the highest purpose of the Internet is to bring us together for empathy and action. After all, the reflector cells and empathy-producing chemicals in our brains only work when we're physically together with all five senses. You can't raise a baby online.”

“I do not suppose that anyone not a poet can realize the agony of creating a poem. Every nerve, even every muscle, seems strained to the breaking point. The poem will not be denied; to refuse to write it would be a greater torture. It tears its way out of the brain, splintering and breaking its passage, and leaves that organ in the state of a jelly-fish when the task is done.”