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“As for the multiple editions, in the case of a truly great writer - Shakespeare, Emily Dickinson, Proust, someone with a canon - there is often a "variorum" edition of the work that presents its variants. I think publishing most other writing that way would be impossible, economically, for publishers, and very ill-advised for authors.”

“Another argument of hope may be drawn from this-that some of the inventions already known are such as before they were discovered it could hardly have entered any man's head to think of; they would have been simply set aside as impossible. For in conjecturing what may be men set before them the example of what has been, and divine of the new with an imagination preoccupied and colored by the old; which way of forming opinions is very fallacious, for streams that are drawn from the springheads of nature do not always run in the old channels.”

“If, then, there must be something eternal, let us see what sort of Being it must be. And to that it is very obvious to Reason, that it must necessarily be a cogitative Being. For it is as impossible to conceive that ever bare incogitative Matter should produce a thinking intelligent Being, as that nothing should of itself produce Matter.”

“People are not prepared or able to rejoice in suffering unless they experience a massive biblical revolution of how they think and feel about the meaning of life. Human nature and American culture make it impossible to rejoice in suffering. This is a miracle in the human soul wrought by God through His Word.”

“You can always find a way to do something. Now, of course, when I do the action, it's an action that inspires people, it's a gift to people, it's not the other way around, I do not take something, I do not hurt people. Yes, I think today would be more than impossible and yet part of me would think that I continue to think that nothing is impossible.”

“What I really think is that our current model of copyright is fundamentally broken. We badly need to replace it with a different system for remunerating creators, which gets it the hell out of the face of the public (who were never aware of it to begin with in the pre-internet dead tree era). Unfortunately, the current copyright model is enshrined in international trade treaty law, making it almost impossible to work around.”

“Oh Young Frankenstein - that's right, Body Heat, Raiders Of The Lost Ark. I mean, you know, it - they just keep going on and on and on - Mission: Impossible. And, you know, I think that the writers are having so much fun now with them that, you know, half the time, you know, people are just sitting around saying - trying to think of what's a great movie to copy.”

“Read Becoming a Writer by Dorothea Brande. Then do what it says, including the tasks you think are impossible. You will particularly hate the advice to write first thing in the morning, but if you can manage it, it might well be the best thing you ever do for yourself. This book is about becoming a writer from the inside out. Many later advice manuals derive from it. You don't ­really need any others, though if you want to boost your confidence, "how to" books seldom do any harm. You can kick-start a whole book with some little writing exercise.”

“Turning a human being into a thing, an object, is almost always the first step towards justifying violence against that person. It is very difficult, perhaps impossible, to be violent to someone we think of as an equal, someone we have empathy with, but it is very easy to abuse a thing”

“In a way, going to Africa allowed me to see possibilities that sometimes seem impossible in certain conditions. It also allowed me to see opportunities for material strategies. I hate it when people think I went and got something [from Africa] and brought it here. It's more about how it affects the way in which I work and affects [my] creativity.”

“The more science learns, the clearer it is that although we are here, we shouldn't be. Once we begin considering the details of it all, the towering odds against our existence begin to become a bit unsettling. When we come to see the superlatively extreme precariousness of our existence, and begin to understand how by any accounting, we ought not to exist, what are we to think or feel? Our existence seems to be not merely a virtually impossible miracle but the most outrageous miracle conceivable, one that makes previously amazing miracles seem like almost nothing.”

“To be and to be creative are synonymous. It is impossible to be and not to be creative. But that impossible thing has happened, that ugly phenomenon has happened, because all your creative sources have been plugged, blocked, destroyed, and your whole energy has been forced into some activity that the society thinks is going to pay.”

“The fact is, I see no compelling reason why we should not unilaterally get rid of our nuclear weapons. To maintain them is costly and adds nothing to our security. I can think of no circumstances under which it would be wise for the United States to use nuclear weapons, even in retaliation for their prior use against us. What, for example, would our targets be? It is impossible to conceive of a target that could be hit without large-scale destruction of many innocent people?”

“Lee was very much his own person so it's impossible to know quite what he would have thought but part of the reason for me staying is that I believe he always wanted this to be a house that would be here forever, that he never wanted his name not to mean anything any more. And I want that too. I want Alexander McQueen to continue. Then, in a hundred years time, there will still be this house that he created, this great place that represents modernity and creativity and beauty and romance and all of those things. That, I think, would be amazing.”

“There's nothing like a deadline to get the old blood flowing. All the juices, really. It doesn't follow, if you think about it. You'd assume certain things ... certain activities ... would become unimportant. Certain betrayals would become unbearable. But they don't really. In fact, quite the opposite. Everything takes on a new light. The impossible becomes possible, desirable even. It's quite remarkable.”

“It was only in South Africa that I got over this shyness, though I never completely overcame it. It was impossible for me to speak impromptu. I hesitated whenever I had to face strange audiences and avoided making a speech whenever I could. Even today I do not think I could or would even be inclined to keep a meeting of friends engaged in idle talk.”

“The view that we know less than we thought we knew about how to change the human condition came, in time, to be called neoconservatism. Many ... , myself included, disliked the term because we did not think we were conservative, neo or paleo. (I voted for John Kennedy, Lyndon Johnson and Hubert Humphrey and worked in the latter's presidential campaign.) It would have been better if we had been called policy skeptics; that is, people who thought it was hard, though not impossible, to make useful and important changes in public policy.”

“I want the music to be heard as close to when I made it, as much as possible. I don't want to get into some "future of the music industry" thing, or where I stand on digital this or that, but I think it's ridiculous that a lot of people in the industry plan so far ahead that it makes a lot of improvisation impossible and makes a lot of people's expectations fixed and not fluid.”

“Every time Mulder smiles, people say, 'God, it was great to see you smile. Mulder never smiles.' I say, 'Mulder smiles a whole lot. He smiles at least once a show.' People get these ideas in their heads and they're impossible to shake. But, to be honest with you, Mulder is every bit as vulnerable and quirky as Ally McBeal. I think Mulder has pretty good legs, too.”

“I've had two great years, probably five good years. So I had 20 years of just kind of uncertainty and suffering and ego destruction and poverty. All these things. There's no way I'm ever going to catch up to the misery years. It's impossible... If I don't do anything dumb or I don't get a disease or something, and then I've got to five to eight years I think where it'll really be great and then it will start to degenerate like uranium, you know?”

“I think that my music is really honest and I think I have something to say. The world revolves around so much negativity that I feel we really need something positive right now. I think people need to be encouraged to strive after those things that seem impossible. That is one of the common themes that runs through my record.”