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“GUNPOWDER, n. An agency employed by civilized nations for the settlement of disputes which might become troublesome if left unadjusted. By most writers the invention of gunpowder is ascribed to the Chinese, but not upon very convincing evidence. Milton says it was invented by the devil to dispel angels with, and this opinion seems to derive some support from the scarcity of angels.”

“Modern man may assert that he can dispense with them, and he may bolster his opinion by insisting that there is no scientific evidence of their truth. But since we are dealing with invisible and unknowable things (for God is beyond human understanding, and there is no mean of proving immortality), why should we bother with evidence?”

“We should listen less to the opinions of those who either overtly promote or stubbornly reject complementary and alternative medicine without acceptable evidence. The many patients who use complementary and alternative medicine deserve better. Patients and healthcare providers need to know which forms are safe and effective. Its future should (and hopefully will) be determined by unbiased scientific evaluation.”

“It is wrong for a man to say that he is certain of the objective truth of any proposition unless he can produce evidence which logically justifies that certainty. This is what Agnosticism asserts; and, in my opinion, it is all that is essential to Agnosticism. That which Agnostics deny and repudiate, as immoral, is the contrary doctrine, that there are propositions which men ought to believe without logically satisfactory evidence; and that reprobation ought to attach to the profession of disbelief in such inadequately supported propositions.”

“Read a work on the "Evidences of Christianity," and it may become highly probable that Christianity, etc., are true. This is an opinion. Feel God. Do His will, till the Absolute Imperative within you speaks as with a living voice, "Thou shalt, and thou shalt not;" and then you do not think, you know that there is a God.”

“That queen, of error, whom we call fancy and opinion, is the more deceitful because she does not always deceive. She would be the infallible rule of truth if she were the infallible rule of falsehood; but being only most frequently in error, she gives no evidence of her real quality, for she marks with the same character both that which is true and that which is false.”

“If an opinion contrary to your own makes you angry, that is a sign that you are subsciously aware of having no good reason for thinking as you do. [...] The most savage controversies are those about matters as to which there is no good evidence either way. Persecution is used in theology, not in arithmetic, because in arithmetic there is knowledge, but in theology there is only opinion. So whenever you find yourself getting angry about a difference of opinion, be on your guard; you will probably find, on examination, that your belief is going beyond what the evidence warrants.”

“Neither logic nor scientific evidence supports such a belief. Although spinal manipulation can relieve certain types of back pain, neck pain, and other musculoskeletal symptoms, there is no scientific evidence that it can restore or maintain health. As a result of expressing my opinion on this subject, I have been called a chiropractic heretic.”

“Although it is easier to find information these days, it is easier than ever before to find misinformation, pseudo-facts, unsupported and fringe opinions, and the like. Children should be taught at an early age what constitutes evidence, how to detect biases or distortions in newspaper accounts, and that there exist hierarchies of information sources. In the medical field, for example, a controlled experiment published in a peer-reviewed journal is a better source than a blog by the Ginseng Growers Association, promoting the health benefits of their own product.”

“In all things, therefore, where we have clear evidence from our ideas, and those principles of knowledge I have above mentioned, reason is the proper judge; and revelation, though it may, in consenting with it, confirm its dictates, yet cannot in such cases invalidate its decrees: nor can we be obliged, where we have the clear and evident sentience of reason, to quit it for the contrary opinion, under a pretence that it is matter of faith: which can have no authority against the plain and clear dictates of reason.”