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“How do they find out with the experiments?''...one way they can find out a whole lot is to make an animal ill and then try different ways to make it better until they find one that works.''But isn't that unkind to the animal?''Well, I suppose it is...but I mean, there isn't a dad anywhere who would hesitate, is there, if he knew it was going to make [his child] better? It's changed the whole world during the last hundred years, and that's no exaggeration.”

“Women who were housewives, who were pretty miserable ... felt inspired by her book and their life changed. They didn't become megastars, but they became a librarian or something. I've heard women say again and again when the subject of Germaine comes up: 'Well, her book changed my life for the better.' And they'll be modest women living pretty ordinary lives, but better lives.”

“On a day of fire and blood, a tattered banner waved above Dumai's wells, bearing the ancient symbol of Aes Sedai. On a day of fire and blood and the one power, as prophecy had suggested, the unstained tower, broken, bent knee to the forgotten sign. The first nine Aes Sedai swore fealty to the Dragon Reborn, and the world was changed forever.”

“I think especially in such an unstable economic environment, what people criticized him [Mitt Romney] for in 2008 his consistency, the fact that he was so strong, and I think people will find that appealing going into the 2012. That’s one of the things that I like about him — because he’s been consistent since he changed his mind.”

“You remember when you were maybe five years old and you went out in the morning and you looked at the day - and it was a very, very beautiful day. You looked at flowers and they were very beautiful flowers. Twenty-five years later, you get up in the morning, you take a look at the flowers - they are wilted. The day isn't a happy day. Well, what's changed? You know they are the same flowers, it's the same world. Something must have changed. Well, probably it was you.”

“Writing is alchemy. Dross becomes gold. Experience is transformed. Pain is changed. Suffering may become song. The ordinary or horrible is pushed by the will of the writer into grace or redemption, a prophetic wail, a screed for justice, an elegy of sadness or sorrow. ... There is always a tension between experience and the thing that finally carries it forward, bears its weight, holds it in. Without that tension, one might as well write a shopping list.”

“When I was younger, I thought, 'Ok, I'm supposed to do this project because it'll help my career,' but that didn't work because I ended up doing movies that I worked really hard on but I didn't really like and they didn't turn out well, so it was like I lost double. Once I just started working with people and projects I believed in, everything changed and I suddenly had a career that I loved and that I was proud of.”

“Examining love is like examining a stocking: if you hold it up to the light and stretch it to search for snags, any snags there are may well run and ruin the stocking. In fact, if I may fashion Coudert's law from Heisenberg's principle of indeterminacy, it is this: Love is not only changed by observation; it is changed for the worse.”

“Relationships help you learn more about what you want. If one doesn't work out, you just kind of look at it and go, Okay, well, this is what I did like and this is what I didn't like, and this is what I did wrong, and maybe I need to be more like this. And so you learn things, and that's why you grow. And you bring all the stuff that you've changed about yourself to a new relationship until you finally find that person you really, really want.”

“I know most of my records are real good but I know that there are definitely things I would've changed at the end of the day. I work on things forever, and there are things I wish I didn't do, but ultimately I know the records are good. I kind of let go of big expectations, maybe because hopefully that means if I don't have them, that it'll do really well, but you just never know.”

“It's kind of interesting to experience that kind of a ride after well, essentially so many years of enjoying a career based on failures and then suddenly something clicks. The weird thing is, I never changed a thing. The process is still the process as it ever was. The fact that people decided to go and see a movie that I was in was probably the most shocking thing that I've ever been through.”

“You mentioned the Navy, for example, and that we have fewer ships than we did in 1916. Well, Governor, we also have fewer horses and bayonets because the nature of our military has changed. We have these things called aircraft carriers where planes land on them. We have these ships that go underwater, nuclear submarines.”

“As well as Japanese animation, technology has a huge influence on Japanese society, and also Japanese novels. It's because before, people tended to think that ideology or religion were the things that actually changed people, but it's been proven that that's not the case. Technology has been proven to be the thing that's actually changing people. So in that sense, it's become a theme in Japanese culture.”

“My spiritual path has largely been Christianity - a label that I embraced and then rejected and have partially embraced again, as my understanding of Christianity has changed over time. When I accepted the mainstream, dogmatic definition of Christianity there came a point when I had to say, "Well, if that's what a Christian is, I'm not one."”

“There used to be a huge snobbism between the film industry and the television industry. I produced and acted in my first - well way back - but the first thing that I produced and acted in was Sarah, Plan and Tall. And the only place to go at the time for really quality television was Hallmark Hall of Fame. And think how much television has changed since then.”

“Well, I think there was a time when I first started that there was such a thing called 'a woman's film' and there were certain scripts that women would make. But I think that's changed a lot now. I think that if a woman director walks into a room with a script, it doesn't really matter what the subject matter is, or the genre is, so long as the financiers feel that the woman has the skills to make the film.”

“If the technology hadn't changed, they [newspapers] would still be great businesses. Network TV [in its heyday], anyone could run and do well. If Tom Murphy as running it, you'd do very well, but even your idiot nephew could do well. Fortunately, carbide cutting tools [such as those made by Iscar] don't have these types of substitutes.”

“When it comes to staying myself - my career isn't my life, it doesn't come home with me. So it's a piece of piss staying grounded and not being changed by it. The same things I've always liked still satisfy me. My team's the same and my group of friends are the same. Of course I'm bowled over by people's response to 21, and when I meet artists I love, it blows my mind. But it baffles me as well. I go home and my best friend laughs at me, rather than going to a celebrity-studded party to rub shoulders with people who know me but who I don't know. I'm Z-list when it comes to that sh**.”

“I don't really have a career as a jazz musician. I don't really have a career as a classical musician. I don't really have a career as a college professor, and yet I did all those things and I did them well. I put out some records in the 1980's and 1990's that changed the way some trumpet players played.”

“Well, God doesn't intervene in many of the situations we would like Him to because He would have to intervene in everything that we say and do that is wrong right the way through to some of the most terrible things happening in nations. What He does is He gives us signs that He is with us and that we can draw help from Him. Jesus changed water into wine. That had no function really. They had already run out of wine in the party so he was only aiding and abetting more drinking.”

“I'm older, wiser and richer, and I still have just as many headaches. It hasn't changed me drastically; certainly, not in terms of relationships. The people I'm close to, and there aren't many of them, have been close for a long time. And we know each other well enough to know it isn't the quantity of time you spend together, it's the quality.”

“Well technology has changed a lot of things, making it possible for just about anyone to make music. But not everybody is a songwriter, so that puts me in a completely different ballpark than the other DJs out here that are writing and producing tracks. I don't stop at tracks, I try to complete the whole package with the song. So working at that level has put me in a completely different place.”