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“The worst side effect of wealth is the social associations it forces on its victims, as people with big houses end up socializing with other people with big houses.”

“I don't think the people today who start hearing voices, stop eating and sleeping, and run amuck are likely to get good treatment. Having more knowledge, better diagnostic capabilities, better medications with fewer side effects, can't make up for the fact that most patients are being treated by doctors, therapists, and hospitals, who are operating under constraints and incentives that reward non-treatment, non-hospitalization, non-therapy, non-follow-up, non-care. Lost to follow-up is the best outcome a health insurer can hope for.”

“In terms of what happened over that hiatus that I took, I just rested. I spent that time with my family, during their really formative years, and enjoyed that, and I messed with pills and new medications that help me to deal with dyskinesia and some other things I was struggling with, that I don't have as much now because of medication to counter the side effects. So, it just seemed like the right time to do it.”

“Industrial vomit...fills our skies and seas. Pesticides and herbicides filter into our foods. Twisted automobile carcasses, aluminum cans, non-returnable glass bottles and synthetic plastics form immense middens in our midst as more and more of our detritus resists decay. We do not even begin to know what to do with our radioactive wastes - whether to pump them into the earth, shoot them into outer space, or pour them into the oceans. Our technological powers increase, but the side effects and potential hazards also escalate.”

“I think that it would be good for people to realize and understand that they are doing something to deal with their pain and they aren't really going to be allowed to escape it and outrun it forever without side effects and certain consequences, as far as emotional and mental happiness and their physical condition. And I'd like people to be aware of those things.”

“Don't aim at success — the more you aim at it and make it a target, the more you are going to miss it. For success, like happiness, cannot be pursued; it must ensue, and it only does so as the unintended side-effect of one's personal dedication to a cause greater than oneself or as the by-product of one's surrender to a person other than oneself. Happiness must happen, and the same holds for success: you have to let it happen by not caring about it. I want you to listen to what your conscience commands you to do and go on to carry it out to the best of your knowledge. Then you will live to see that in the long run — in the long run, I say — success will follow you precisely because you had forgotten to think of it.”

“The Great Society went wrong for three major reasons. First, the self-organization the Johnson administration promoted turned out to be not the pooling of family and community resources into shops and businesses, but political pressure for government handouts. Second, the Great Society failed to anticipate the perverse side-effects of handing money out to people who have done nothing to earn it. Third, while the Great Society was showering money on the poor, the Supreme Court was with childlike glee smashing to bits traditional methods of maintaining law and order.”

“Realistically, there is a danger, of course, when you're going into someone's living room as the same guy every week. But I don't fear it because, I mean, there's really nothing I can do about it. I can try to combat it through the work, and maybe make sure I don't do Sheldon 2.0 in any other projects. But it's just really hard for me to find any negative side effects from this experience.”