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“Combining in our survey then, the whole range of deposits from the most recent to the most ancient group, how striking a succession do they present:- so various yet so uniform-so vast yet so connected. In thus tracing back to the most remote periods in the physical history of our continents, one system of operations, as the means by which many complex formations have been successively produced, the mind becomes impressed with the singleness of nature's laws; and in this respect, at least, geology is hardly inferior in simplicity to astronomy.”

“You may object that by speaking of simplicity and beauty I am introducing aesthetic criteria of truth, and I frankly admit that I am strongly attracted by the simplicity and beauty of mathematical schemes which nature presents us. You must have felt this too: the almost frightening simplicity and wholeness of the relationship, which nature suddenly spreads out before us.”

“During the time that [Karl] Landsteiner gave me an education in the field of imununology, I discovered that he and I were thinking about the serologic problem in very different ways. He would ask, What do these experiments force us to believe about the nature of the world? I would ask, What is the most. simple and general picture of the world that we can formulate that is not ruled by these experiments? I realized that medical and biological investigators were not attacking their problems the same way that theoretical physicists do, the way I had been in the habit of doing.”

“I have often had cause to feel that my hands are cleverer than my head. That is a crude way of characterizing the dialectics of experimentation. When it is going well, it is like a quiet conversation with Nature. One asks a question and gets an answer, then one asks the next question and gets the next answer. An experiment is a device to make Nature speak intelligibly. After that, one only has to listen.”

“Only by following out the injunction of our great predecessor [William Harvey] to search out and study the secrets of Nature by way of experiment, can we hope to attain to a comprehension of 'the wisdom of the body and the understanding of the heart,' and thereby to the mastery of disease and pain, which will enable us to relieve the burden of mankind.”

“Our present work sets forth mathematical principles of philosophy. For the basic problem of philosophy seems to be to discover the forces of nature from the phenomena of motions and then to demonstrate the other phenomena from these forces. It is to these ends that the general propositions in books 1 and 2 are directed, while in book 3 our explanation of the system of the world illustrates these propositions.”

“The great revelation of the quantum theory was that features of discreteness were discovered in the Book of Nature, in a context in which anything other than continuity seemed to be absurd according to the views held until then.”

“We are very lucky to be living in an age in which we are still making discoveries. It is like the discovery of America-you only discover it once. The age in which we live is the age in which we are discovering the fundamental laws of nature, and that day will never come again. It is very exciting, it is marvelous, but this excitement will have to go.”

“The physician heals, Nature makes well.”

“"Pieces" almost always appear 'as parts' in whole processes. ... To sever a "'part" from the organized whole in which it occurs-whether it itself be a subsidiary whole or an "element"-is a very real process usually involving alterations in that "part". Modifications of a part frequently involve changes elsewhere in the whole itself. Nor is the nature of these alterations arbitrary, for they too are determined by whole-conditions.”

“Amid all the revolutions of the globe, the economy of Nature has been uniform, ... and her laws are the only things that have resisted the general movement. The rivers and the rocks, the seas and the continents, have been changed in all their parts; but the laws which direct those changes, and the rules to which they are subject, have remained invariably the same.”

“Among the older records, we find chapter after chapter of which we can read the characters, and make out their meaning: and as we approach the period of man's creation, our book becomes more clear, and nature seems to speak to us in language so like our own, that we easily comprehend it. But just as we begin to enter on the history of physical changes going on before our eyes, and in which we ourselves bear a part, our chronicle seems to fail us-a leaf has been torn out from nature's record, and the succession of events is almost hidden from our eyes.”

“Coy Nature, (which remain'd, though aged grown, A beauteous virgin still, enjoy'd by none, Nor seen unveil'd by anyone), When Harvey's violent passion she did see, Began to tremble and to flee; Took sanctuary, like Daphne, in a tree: There Daphne's Lover stopped, and thought it much The very leaves of her to touch: But Harvey, our Apollo, stopp'd not so; Into the Bark and Root he after her did go!”

“Ecologically speaking, a spilt tanker load is like sticking a safety pin into an elephant's foot. The planet barely notices. After the Exxon Valdez accident in Alaska the oil company spent billions tidying up the coastline, but it was a waste of money because the waves were cleaning up faster than Exxon could. Environmentalists can never accept the planet's ability to self-heal.”

“God put a secret art into the forces of Nature so as to enable it to fashion itself out of chaos into a perfect world system.”

“I would beg the wise and learned fathers (of the church) to consider with all diligence the difference which exists between matters of mere opinion and matters of demonstration. ... [I]t is not in the power of professors of the demonstrative sciences to alter their opinions at will, so as to be now of one way of thinking and now of another. ... [D]emonstrated conclusions about things in nature of the heavens, do not admit of being altered with the same ease as opinions to what is permissible or not, under a contract, mortgage, or bill of exchange.”

“In so far as such developments utilise the natural energy running to waste, as in water power, they may be accounted as pure gain. But in so far as they consume the fuel resources of the globe they are very different. The one is like spending the interest on a legacy, and the other is like spending the legacy itself. ... [There is] a still hardly recognised coming energy problem.”

“It be urged that the wild and uncultivated tree, hitherto yielding sour and bitter fruit only, can never be made to yield better; yet we know that the grafting art implants a new tree on the savage stock, producing what is most estimable in kind and degree. Education, in like manner, engrafts a new man on the native stock, and improves what in his nature was vicious and perverse into qualities of virtue and social worth.”

“It can hardly be pressed forcibly enough on the attention of the student of nature, that there is scarcely any natural phenomenon which can be fully and completely explained, in all its circumstances, without a union of several, perhaps of all, the sciences.”

“It must be for truth's sake, and not for the sake of its usefulness to humanity, that the scientific man studies Nature. The application of science to the useful arts requires other abilities, other qualities, other tools than his; and therefore I say that the man of science who follows his studies into their practical application is false to his calling. The practical man stands ever ready to take up the work where the scientific man leaves it, and adapt it to the material wants and uses of daily life.”

“It troubles me that we are so easily pressured by purveyors of technology into permitting so-called "progress" to alter our lives without attempting to control it-as if technology were an irrepressible force of nature to which we must meekly submit.”

“Kant, discussing the various modes of perception by which the human mind apprehends nature, concluded that it is specially prone to see nature through mathematical spectacles. Just as a man wearing blue spectacles would see only a blue world, so Kant thought that, with our mental bias, we tend to see only a mathematical world.”