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“The general public doesn't know and probably doesn't care about punctuated equilibria nor indeed should they, or the greenhouse effect on some other planet - they barely have the ability to cope with the greenhouse effect on their own planet. So I think you have to distinguish between the broad visibility of a scientist when he or she is speaking to a general public and trying to address general issues and the continued position that a scientist may have into the history of a particular subject.”

“I have sat with the mothers who have lost addicted sons. I have sat with families of kids who have been killed in drug-related gang violence. I have been to the prisons. I have seen the effects. At some point in time, I felt I had to do something other than write a novel about it, that I needed to try to make some sort of contribution, at least try to make some sort of difference in the real world.”

“If you are walking down the street, camera in your hand, loaded and ready to shoot. You see a person falling from a high building, either having fallen or jumped. That person is falling through space. You don't shoot that photograph unless the theme you are working on has to do with the effects of space on the human figure. If you simply photograph that event because it is an event that is happening, you're doing photojournalism.”

“A visionary company is like a great work of art. Think of Michelangelo's scenes from Genesis on the ceiling of the Sistine Chapel or his statue of David. Think of a great and enduring novel like Huckleberry Finn or Crime and Punishment. Think of Beethoven's Ninth Symphony or Shakespeare's Henry V. Think of a beautifully designed building, like the masterpieces of Frank Lloyd Wright or Ludwig Mies van der Rohe. You can't point to any one single item that makes the whole thing work; it's the entire work-all the pieces working together to create an overall effect-that leads to enduring greatness.”

“For every advance that the Japanese have made since they started their frenzied career of conquest, they have had to pay a very heavy toll in warships, in transports, in planes, and in men. They are feeling the effects of those losses.”

“I believe that should is one of the most damaging words in our language. Every time we use it, we are, in effect, saying that we are wrong, or we were wrong, or we're going to be wrong. I would like to take the word should out of our vocabulary forever and replace it with the word could. This word gives us a choice, and we're never wrong.”

“And there was a deeper, less visible effect of the Truman loyalty program. Seeing its consequences for certain individuals and fearing its intrusion on their own lives, many in the government sought protection by strongly asserting their anti-Communism. In the public action that ensued, policy was based not on reality but, instinctively or deliberately, on personal caution...Those who urged a militant and sometimes military anti-Communism were considered sound, trustworthy and personally safe; those who questioned such a course were politically unsafe, possible even slightly disloyal.”

“The effect of speech upon the condition of the soul is comparable to the power of drugs over the nature of bodies. For just as different drugs dispel different secretions from the body, and some bring an end to disease and others to life, so also in the case of speeches, some distress, others delight, some cause fear, others make the hearers bold, and some drug and bewitch the soul with a kind of evil persuasion.”

“But for the present I would lie there and know I didn't have to get up, and feel the holy emptiness and blessed fatigue of a saint after the dark night of the soul. For God and Nothing have a lot in common. You look either one of Them straight in the eye for a second and the immediate effect on the human constitution is the same.”

“The worst of this ever growing cancer of Statism [ie big 'paternal' government - socialism, communism and fascism] is its moral effect. The country is rich enough to stand its frightful economic wastage for a long time yet, and still prosper, but it is already so poverty-stricken in its moral resources that the present drain will quickly run them out.”

“When Martha first met me, I was anxious and jumpy. I was always tapping my foot, rocking, or exhibiting some other behavioral aberration. Of course, now we know that's just normal Aspergian behavior, but back then other people thought it was weird, so of course I did, too. One day, for some reason, she decided to try petting my arm, and I immediately stopped rocking and fidgeting. The result was so dramatic, she never stopped. It didn't take long for me to realize the calming effect, too. I like being petted and scratched. "Can you pet me?" I say when I sit next to her.”

“I don't think the people today who start hearing voices, stop eating and sleeping, and run amuck are likely to get good treatment. Having more knowledge, better diagnostic capabilities, better medications with fewer side effects, can't make up for the fact that most patients are being treated by doctors, therapists, and hospitals, who are operating under constraints and incentives that reward non-treatment, non-hospitalization, non-therapy, non-follow-up, non-care. Lost to follow-up is the best outcome a health insurer can hope for.”