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“As the dominant social ethic changed from a religious to a secular one, the problem of heresy disappeared, and the problem of madness arose and became of great social significance. In the next chapter I shall examine the creation of social deviants, and shall show that as formerly priests had manufactured heretics, so physicians, as the new guardians of social conduct and morality, began to manufacture madmen.”

“We have entered a new and different world-richly interconnected and radically multicentric-in which the traditional holders of power have to move over and make room for new stakeholders, new players, and new leaders of many kinds. Nobody in Charge, drawing on the learnings of a wise and widely experienced public executive, offers some priceless insights into how things have changed, where they are now, and where we may be going next in this bewildering terrain.”

“Communication has changed so rapidly in the last 20 years, it's almost impossible to predict what might occur even in the next decade. E-mail, which now sends data hurtling across vast distances at the speed of light, has replaced primitive forms of communication such as smoke signals, which sent data hurtling across vast distances at the speed of light.”

“I was appointed U.S. attorney by President [George] Bush on September 10th, 2001, and the world changed enormously the next day, and that happened in my state.I will make no apologies, ever, for protecting the lives and the safety of the American people. We have to give more tools to our folks to be able to do that, not fewer, and then trust those people and oversee them to do it the right way.”

“I think people like listening to what I call trippy music but maybe next year it will be something else. I still have gangster tracks and real-life stories and situations in my music. I’ve been blessed because over 20 year, I never stopped doing what I was doing. It’s pretty much the same thing and I’ve never really changed anything up.”

“The iPod is clearly a tipping point (and I'm not quite sure it is a wholly positive development), because it is a revolution in the way that we consume creative property, which I would call art. It has radically changed the relationship between the artist and the audience, how money changes hands, and how much money changes hands. Music was the first, and books are coming next. The Kindle or some form of electronic book is clearly inevitable, and it will massively reshape how books are sold, who pays for them, and how they're consumed. It is going to be really fascinating.”

“I feel like that [the role in Star Trek] is a prime example of, yeah, I got that role and it was awesome, because it changed a lot for me professionally, but then creatively, it became a whole other thing, with J.J. [Abrams] and Chris [Pine] and the people I got to know. Now I just feel like it's our jobs to be open and to keep moving stuff forward. I don't know what that means. This is the first time in a long time that I have no idea what's happening next. As scary as that is, and as anxiety-provoking as that can still be, it's also really exciting.”